LISTE DER PUBLIKATIONEN AUS DER TRANSFUSIONSMEDIZIN

1.    Deciphering VITT's dangerous code.
Bakchoul T, Zlamal J.
Blood. 2024 Jan 25;143(4):301-303. doi: 10.1182/blood.2023023141.
PMID: 38270945 No abstract available.

2.    Accuracy of Diagnosing Heparin-Induced Thrombocytopenia.
Larsen EL, Nilius H, Studt JD, Tsakiris DA, Greinacher A, Mendez A, Schmidt A, Wuillemin WA, Gerber B, Vishnu P, Graf L, Kremer Hovinga JA, Goetze JP, Bakchoul T, Nagler M.
JAMA Netw Open. 2024 Mar 4;7(3):e243786. doi:
10.1001/jamanetworkopen.2024.3786.
PMID: 38530310 Free PMC article.

3.    Cerebral venous sinus thrombosis and thrombocytopenia due to heparin-independent anti-PF4 antibodies after adenovirus infection.
Uzun G, Zlamal J, Althaus K, Bevot A, Hennersdorf F, Wolska N, Jock A, Kern J, Icheva V, Poli S, Ernemann U, Neu A, Bakchoul T.
Haematologica. 2024 Jun 1;109(6):2010-2015. doi:
10.3324/haematol.2023.284127.
PMID: 37881869 Free PMC article. No abstract available.

4.    In vitro Hemostatic Functions of Cold-Stored Platelets.
Kirschall J, Uzun G, Bakchoul T, Marini I.
Transfus Med Hemother. 2023 Nov 16;51(2):94-100. doi:
10.1159/000533735. eCollection 2024 Apr.
PMID: 38584694 Free PMC article. Review.

5.    Proteomic profiling for biomarker discovery in heparin-induced thrombocytopenia.
Nilius H, Hamzeh-Cognasse H, Hastings J, Studt JD, Tsakiris DA, Greinacher A, Mendez A, Schmidt A, Wuillemin WA, Gerber B, Vishnu P, Graf L, Kremer Hovinga JA, Bakchoul T, Cognasse F, Nagler M.
Blood Adv. 2024 Jun 11;8(11):2825-2834. doi:
10.1182/bloodadvances.2024012782.
PMID: 38588487 Free PMC article.

6.    Semaphorin 7A coordinates neutrophil response during pulmonary inflammation and sepsis.
Granja T, Köhler D, Tang L, Burkard P, Eggstein C, Hemmen K, Heinze KG, Heck-Swain KL, Koeppen M, Günther S, Blaha M, Magunia H, Bamberg M, Konrad F, Ngamsri KC, Fuhr A, Keller M, Bernard AM, Haeberle HA, Bakchoul T, Zarbock A, Nieswandt B, Rosenberger P.
Blood Adv. 2024 Jun 11;8(11):2660-2674. doi:
10.1182/bloodadvances.2023011778.
PMID: 38489236 Free PMC article.  

7.    Diagnostic value of antibody-induced procoagulant platelets in heparin-induced thrombocytopenia: communication from the ISTH SSC Subcommittee on Platelet Immunology.
Zlamal J, Aliotta A, Alberio L, Chen V, Bakchoul T; SSC Platelet Immunology of the ISTH.
J Thromb Haemost. 2024 Mar;22(3):860-868. doi:
10.1016/j.jtha.2023.11.019. Epub 2023 Dec 7.
PMID: 38065529

8.    Heparin-activated procoagulant platelet assay: a flow cytometry-based functional test for heparin-induced thrombocytopenia.
Pelzl L, Uzun G, Marini I, Zlamal J, Trumpp PN, Karakuyu A, Bakchoul T, Althaus K.
J Thromb Haemost. 2024 Feb;22(2):470-479. doi: 10.1016/j.jtha.2023.10.003. Epub 2023 Oct 13.
PMID: 37838242

9.    Reducing the global burden of cerebral venous thrombosis: An international research agenda.
Coutinho JM, van de Munckhof A, Aguiar de Sousa D, Poli S, Aaron S, Arauz A, Conforto AB, Krzywicka K, Hiltunen S, Lindgren E, Sánchez van Kammen M, Shu L, Bakchoul T, Belder R, van den Berg R, Boumans E, Cannegieter S, Cano-Nigenda V, Field TS, Fragata I, Heldner MR, Hernández-Pérez M, Klok FA, Leker RR, Lucas-Neto L, Molad J, Nguyen TN, Saaltink DJ, Saposnik G, Sharma P, Stam J, Thijs V, van der Vaart M, Werring DJ, Wong Ramos D, Yaghi S, Yeşilot N, Tatlisumak T, Putaala J, Jood K, Arnold M, Ferro JM.
Int J Stroke. 2024 Jul;19(6):599-610. doi: 10.1177/17474930241242266. Epub 2024 Apr 9.
PMID: 38494462 Free PMC article. Review.

10.    Results of an international survey of opinions on the definitions and treatments for heparin-induced thrombocytopenia: communication from the ISTH SSC Subcommittee on Platelet Immunology.
Choi PY, Uzun G, Bakchoul T; SSC Platelet Immunology of the ISTH.
J Thromb Haemost. 2024 Jun;22(6):1772-1778. doi:
10.1016/j.jtha.2024.01.014. Epub 2024 Jan 30.
PMID: 38301999

11.    Antithrombotic Therapy in Cancer Patients with Cardiovascular Diseases: Daily Practice Recommendations by the Hemostasis Working Party of the German Society of Hematology and Medical Oncology (DGHO) and the Society for Thrombosis and Hemostasis Research (GTH e.V.).
Parmentier S, Koschmieder S, Henze L, Griesshammer M, Matzdorff A, Bakchoul T, Langer F, Alesci RS, Duerschmied D, Thomalla G, Riess H. Hamostaseologie. 2024 Jul 15. doi: 10.1055/a-2337-4025. Online ahead of print. 
PMID: 39009011  

12.    ISTH bleeding assessment tool and platelet function analyzer in children with mild inherited platelet function disorders.
Alhaj D, Hagedorn N, Cuntz F, Reschke M, Schuldes J, Ruthenberg J, Bakchoul T, Greinacher A, Holzhauer S.
Eur J Haematol. 2024 Jul;113(1):54-65. doi: 10.1111/ejh.14198. Epub 2024 Mar 28.
PMID: 38549165

13.    Characteristics Associated with COVID-19 Breakthrough Infections after Booster Vaccinations in Healthcare Workers: Insights from the TüSeRe:exact Study.
Uzun G, Bareiß A, Becker M, Althaus K, Dulovic A, Junker D, Schenke-Layland K, Martus P, Borst O, Schneiderhan-Marra N, Bakchoul T.
J Clin Med. 2024 Mar 9;13(6):1571. doi: 10.3390/jcm13061571.
PMID: 38541797 Free PMC article.

14.    Prospective, international, multisite comparison of platelet isolation techniques for genome-wide transcriptomics: communication from the SSC of the ISTH.
Banerjee M, Rowley JW, Stubben CJ, Tolley ND, Freson K, Nelson B, Nagy B Jr, Fejes Z, Blair AM, Turro E, Gresele P, Taranta GC, Bury L, Falcinelli E, Lordkipanidzé M, Alessi MC, Johnson AD, Bakchoul T, Ramstrom S, Frontini M, Camera M, Brambilla M, Campbell RA, Rondina MT.
J Thromb Haemost. 2024 Jul 3:S1538-7836(24)00376-3. doi:
10.1016/j.jtha.2024.06.017. Online ahead of print.
PMID: 38969303

 

PubMed Results 2023

 

1.    In vitro Hemostatic Functions of Cold-Stored Platelets.
Kirschall J, Uzun G, Bakchoul T, Marini I.
Transfus Med Hemother. 2023 Nov 16;51(2):94-100. doi: 10.1159/000533735. eCollection 2024 Apr.
PMID: 38584694 Free PMC article. Review.

2.    Diagnostic value of antibody-induced procoagulant platelets in heparin-induced thrombocytopenia: communication from the ISTH SSC Subcommittee on Platelet Immunology. Zlamal J, Aliotta A, Alberio L, Chen V, Bakchoul T; SSC Platelet Immunology of the ISTH.
J Thromb Haemost. 2024 Mar;22(3):860-868. doi: 10.1016/j.jtha.2023.11.019. Epub 2023 Dec 7.
PMID: 38065529

3.    Heparin-activated procoagulant platelet assay: a flow cytometry-based functional test for heparin-induced thrombocytopenia.
Pelzl L, Uzun G, Marini I, Zlamal J, Trumpp PN, Karakuyu A, Bakchoul T, Althaus K.
J Thromb Haemost. 2024 Feb;22(2):470-479. doi: 10.1016/j.jtha.2023.10.003. Epub 2023 Oct 13.
PMID: 37838242

4.    Sex differences in cerebral venous sinus thrombosis after adenoviral vaccination against COVID-19.
Scutelnic A, van de Munckhof A, Krzywicka K, van Kammen MS, Lindgren E, Cordonnier C, Kleinig TJ, Field TS, Poli S, Lemmens R, Middeldorp S, Aaron S, Borhani-Haghighi A, Arauz A, Kremer Hovinga JA, Günther A, Putaala J, Wasay M, Conforto AB, de Sousa DA, Jood K, Tatlisumak T, Ferro JM, Coutinho JM, Arnold M, Heldner MR; Cerebral Venous Sinus Thrombosis with Thrombocytopenia Syndrome Study Group**.
Eur Stroke J. 2023 Dec;8(4):1001-1010. doi: 10.1177/23969873231185213. Epub 2023 Jul 11. PMID: 37434312 Free PMC article.

5.    Inhibition of GPIb-α-mediated apoptosis signaling enables cold storage of platelets.
Marini I, Pelzl L, Tamamushi Y, Maettler CT, Witzemann A, Althaus K, Nowak-Harnau S, Seifried E, Bakchoul T.
Haematologica. 2023 Nov 1;108(11):2959-2971. doi: 10.3324/haematol.2022.282572.
PMID: 37345472 Free PMC article.

6.    Cerebral venous sinus thrombosis and thrombocytopenia due to heparin-independent anti-PF4 antibodies after adenovirus infection.
Uzun G, Zlamal J, Althaus K, Bevot A, Hennersdorf F, Wolska N, Jock A, Kern J, Icheva V, Poli S, Ernemann U, Neu A, Bakchoul T.
Haematologica. 2023 Oct 26. doi: 10.3324/haematol.2023.284127. Online ahead of print.
PMID: 37881869  

7.    Cooling Platelets Down in Antibody-Mediated Immunothrombosis.
Bakchoul T, Wolska N.
Arterioscler Thromb Vasc Biol. 2023 Oct;43(10):1833-1835. doi:
10.1161/ATVBAHA.123.319738. Epub 2023 Aug 31.
PMID: 37650328 No abstract available.

8.    Consensus report on flow cytometry for platelet function testing in thrombocytopenic patients: communication from the SSC of the ISTH.
Jourdi G, Ramström S, Sharma R, Bakchoul T, Lordkipanidzé M; FC-PFT in TP study group.
J Thromb Haemost. 2023 Oct;21(10):2941-2952. doi: 10.1016/j.jtha.2023.07.006. Epub 2023 Jul 20.
PMID: 37481072 Review.

9.    Cerebral venous sinus thrombosis due to vaccine-induced immune thrombotic thrombocytopenia in middle-income countries.
van de Munckhof A, Borhani-Haghighi A, Aaron S, Krzywicka K, van Kammen MS, Cordonnier C, Kleinig TJ, Field TS, Poli S, Lemmens R, Scutelnic A, Lindgren E, Duan J, Arslan Y, van Gorp EC, Kremer Hovinga JA, Günther A, Jood K, Tatlisumak T, Putaala J, Heldner MR, Arnold M, de Sousa DA, Wasay M, Arauz A, Conforto AB, Ferro JM, Coutinho JM; Cerebral Venous Sinus Thrombosis with Thrombocytopenia Syndrome Study Group.
Int J Stroke. 2023 Oct;18(9):1112-1120. doi: 10.1177/17474930231182901. Epub 2023 Jun 30.
PMID: 37277922 Free PMC article.

10.     Platelet phosphatidylserine is the critical mediator of thrombosis in heparin-induced thrombocytopenia.
Zlamal J, Singh A, Weich K, Jaffal H, Uzun G, Pelzl L, Althaus K, Bakchoul T.
Haematologica. 2023 Oct 1;108(10):2690-2702. doi: 10.3324/haematol.2022.282275.
PMID: 37102605 Free PMC article.

11.    Limited concordance of heparin/platelet factor 4 antibody assays for the diagnosis of heparin-induced thrombocytopenia: an analysis of the TORADI-HIT study.
Hammerer-Lercher A, Nilius H, Studt JD, Tsakiris DA, Greinacher A, Mendez A, Schmidt A, Wuillemin WA, Gerber B, Kremer Hovinga JA, Vishnu P, Graf L, Bakchoul T, Nagler M.
J Thromb Haemost. 2023 Sep;21(9):2559-2568. doi: 10.1016/j.jtha.2023.05.016. Epub 2023 May 27.
PMID: 37247669

PubMed Results 2022

1.    Treatment of drug-induced immune thrombocytopenias.
Marini I, Uzun G, Jamal K, Bakchoul T.
Haematologica. 2022 Jun 1;107(6):1264-1277. doi:
10.3324/haematol.2021.279484.
PMID: 35642486 Free PMC article. Review.

2.    Vaccinations and ITP: keep on track(ing).
Bakchoul T, Singh A.
Blood. 2022 Mar 10;139(10):1437-1438. doi: 10.1182/blood.2021014193. PMID: 35267007 Free PMC article. No abstract available.

3.    GWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements.
Dixon PH, Levine AP, Cebola I, Chan MMY, Amin AS, Aich A, Mozere M, Maude H, Mitchell AL, Zhang J; NIHR BioResource; Genomics England Research Consortium Collaborators; Chambers J, Syngelaki A, Donnelly J, Cooley S, Geary M, Nicolaides K, Thorsell M, Hague WM, Estiu MC, Marschall HU, Gale DP, Williamson C.
Nat Commun. 2022 Aug 17;13(1):4840. doi: 10.1038/s41467-022-29931-z. PMID: 35977952 Free PMC article.

4.    Immune-Mediated Platelet Activation in COVID-19 and Vaccine-Induced Immune Thrombotic Thrombocytopenia.
Uzun G, Pelzl L, Singh A, Bakchoul T.
Front Immunol. 2022 Feb 22;13:837629. doi: 10.3389/fimmu.2022.837629. eCollection 2022.
PMID: 35273612 Free PMC article. Review.

5.    Diagnosis of Platelet Function Disorders: A Challenge for Laboratories. Wagner M, Uzun G, Bakchoul T, Althaus K.
Hamostaseologie. 2022 Feb;42(1):36-45. doi: 10.1055/a-1700-7036. Epub 2022 Feb 23.
PMID: 35196730 Review.

6.    Proteomic profiling for biomarker discovery in heparin-induced thrombocytopenia.
Nilius H, Hamzeh-Cognasse H, Hastings J, Studt JD, Tsakiris DA, Greinacher A, Mendez A, Schmidt A, Wuillemin WA, Gerber B, Vishnu P, Graf L, Kremer Hovinga JA, Bakchoul T, Cognasse F, Nagler M.
Blood Adv. 2024 Jun 11;8(11):2825-2834. doi:
10.1182/bloodadvances.2024012782.
PMID: 38588487 Free PMC article.

7.    Assessment and Monitoring of Coagulation in Patients with COVID-19: A Review of Current Literature.
Uzun G, Althaus K, Hammer S, Bakchoul T.
Hamostaseologie. 2022 Dec;42(6):409-419. doi: 10.1055/a-1755-8676. Epub 2022 Apr 27.
PMID: 35477118 Review.

8.    Cerebral venous sinus thrombosis due to vaccine-induced immune thrombotic thrombocytopenia in middle-income countries.
van de Munckhof A, Borhani-Haghighi A, Aaron S, Krzywicka K, van Kammen MS, Cordonnier C, Kleinig TJ, Field TS, Poli S, Lemmens R, Scutelnic A, Lindgren E, Duan J, Arslan Y, van Gorp EC, Kremer Hovinga JA, Günther A, Jood K, Tatlisumak T, Putaala J, Heldner MR, Arnold M, de Sousa DA, Wasay M, Arauz A, Conforto AB, Ferro JM, Coutinho JM; Cerebral Venous Sinus Thrombosis with Thrombocytopenia Syndrome Study Group.
Int J Stroke. 2023 Oct;18(9):1112-1120. doi: 10.1177/17474930231182901. Epub 2023 Jun 30.
PMID: 37277922 Free PMC article.

9.    Upregulation of cAMP prevents antibody-mediated thrombus formation in COVID-19.
Zlamal J, Althaus K, Jaffal H, Häberle H, Pelzl L, Singh A, Witzemann A, Weich K, Bitzer M, Malek N, Göpel S, Bösmüller H, Gawaz M, Mirakaj V, Rosenberger P, Bakchoul T.
Blood Adv. 2022 Jan 11;6(1):248-258. doi:
10.1182/bloodadvances.2021005210.
PMID: 34753174 Free PMC article.

10.    Antibody-mediated procoagulant platelet formation in COVID-19 is AKT dependent.
Pelzl L, Singh A, Funk J, Witzemann A, Marini I, Zlamal J, Weich K, Abou-Khalel W, Hammer S, Uzun G, Althaus K, Bakchoul T.
J Thromb Haemost. 2022 Feb;20(2):387-398. doi: 10.1111/jth.15587. Epub 2021 Dec 3.
PMID: 34752677 Free PMC article.

11.    The interaction between anti-PF4 antibodies and anticoagulants in vaccine-induced thrombotic thrombocytopenia.
Singh A, Toma F, Uzun G, Wagner TR, Pelzl L, Zlamal J, Freytag V, Weich K, Nowak-Harnau S, Rothbauer U, Althaus K, Bakchoul T.
Blood. 2022 Jun 9;139(23):3430-3438. doi: 10.1182/blood.2021013839. PMID: 35679071 Free PMC article.

12.    Platelet ACKR3/CXCR7 favors antiplatelet lipids over an atherothrombotic lipidome and regulates thromboinflammation.
Cebo M, Dittrich K, Fu X, Manke MC, Emschermann F, Rheinlaender J, von Eysmondt H, Ferreirós N, Sudman J, Witte A, Pelzl L, Borst O, Geisler T, Rath D, Bakchoul T, Gawaz M, Schäffer TE, Lämmerhofer M, Chatterjee M. Blood. 2022 Mar 17;139(11):1722-1742. doi: 10.1182/blood.2021013097. PMID: 34905596  

13.    Increased plasma level of soluble P-selectin in non-hospitalized COVID-19 convalescent donors.
Müller R, Rink G, Uzun G, Bakchoul T, Wuchter P, Klüter H, Bugert P. Thromb Res. 2022 Aug;216:120-124. doi: 10.1016/j.thromres.2022.06.014. Epub 2022 Jul 5.
PMID: 35810548 Free PMC article.

14.    Vaccine Side Effects in Health Care Workers after Vaccination against SARS-CoV-2: Data from TüSeRe:exact Study.
Bareiß A, Uzun G, Mikus M, Becker M, Althaus K, Schneiderhan-Marra N, Fürstberger A, Schwab JD, Kestler HA, Holderried M, Martus P, Schenke-Layland K, Bakchoul T.
Viruses. 2022 Dec 25;15(1):65. doi: 10.3390/v15010065.
PMID: 36680106 Free PMC article.

15.    Organ Donation From a Brain Dead Donor With Vaccine-induced Immune Thrombotic Thrombocytopenia After Ad26.COV2.S: The Risk of Organ Microthrombi.
Uzun G, Bohnert BN, Althaus K, Nann D, Nadalin S, Heyne N, Fend F, Haap M, Bakchoul T.
Transplantation. 2022 Mar 1;106(3):e178-e180. doi:
10.1097/TP.0000000000004039.
PMID: 34974451 Free PMC article. No abstract available.

16.    Platelets and Sera from Donors of Convalescent Plasma after Mild COVID-19 Show No Procoagulant Phenotype.
Uzun G, Singh A, Abou-Khalel W, Pelzl L, Weich K, Nowak-Harnau S, Althaus K, Bugert P, Klüter H, Bakchoul T.
Hamostaseologie. 2022 Oct;42(S 01):S14-S23. doi: 10.1055/a-1797-0564. Epub 2022 Oct 26.
PMID: 36288732

17.    A machine-learning model for reducing misdiagnosis in heparin-induced thrombocytopenia: A prospective, multicenter, observational study.
Nilius H, Cuker A, Haug S, Nakas C, Studt JD, Tsakiris DA, Greinacher A, Mendez A, Schmidt A, Wuillemin WA, Gerber B, Kremer Hovinga JA, Vishnu P, Graf L, Kashev A, Sznitman R, Bakchoul T, Nagler M.
EClinicalMedicine. 2022 Nov 24;55:101745. doi:
10.1016/j.eclinm.2022.101745. eCollection 2023 Jan.
PMID: 36457646 Free PMC article.

18.    One-year follow-up of the CAPSID randomized trial for high-dose convalescent plasma in severe COVID-19 patients.
Körper S, Grüner B, Zickler D, Wiesmann T, Wuchter P, Blasczyk R, Zacharowski K, Spieth P, Tonn T, Rosenberger P, Paul G, Pilch J, Schwäble J, Bakchoul T, Thiele T, Knörlein J, Dollinger MM, Krebs J, Bentz M, Corman VM, Kilalic D, Schmidtke-Schrezenmeier G, Lepper PM, Ernst L, Wulf H, Ulrich A, Weiss M, Kruse JM, Burkhardt T, Müller R, Klüter H, Schmidt M, Jahrsdörfer B, Lotfi R, Rojewski M, Appl T, Mayer B, Schnecko P, Seifried E, Schrezenmeier H.
J Clin Invest. 2022 Dec 15;132(24):e163657. doi: 10.1172/JCI163657.
PMID: 36326824 Free PMC article. Clinical Trial.

19.    Anti-PF4 testing for vaccine-induced immune thrombocytopenia and thrombosis (VITT): Results from a NEQAS, ECAT and SSC collaborative exercise in 385 centers worldwide.
Reilly-Stitt C, Jennings I, Kitchen S, Makris M, Meijer P, de Maat M, Scully M, Bakchoul T, Walker ID.
J Thromb Haemost. 2022 Aug;20(8):1875-1879. doi: 10.1111/jth.15766. Epub 2022 Jun 6.
PMID: 35603519

20.    Multicentre evaluation of 5B9, a monoclonal anti-PF4/heparin IgG mimicking human HIT antibodies, as an internal quality control in HIT functional assays: Communication from the ISTH SSC Subcommittee on Platelet Immunology. Pouplard C, Rollin J, Vayne C, Charuel N, Ahmadi Z, Alberio L, Azjenberg N, Althaus K, Bakchoul T, Chong B, Curtis BR, Faille D, Gomez FJ, Gresele P, Morel-Kopp MC, Mullier F, Nazy I, Smith JW, Greinacher A, Gruel Y.
J Thromb Haemost. 2022 Jan;20(1):252-259. doi: 10.1111/jth.15560. Epub 2021 Nov 3.
PMID: 34657390

21.    Characterization of Shear Stress Mediated Platelet Dysfunction: Data from an Ex Vivo Model for Extracorporeal Circulation and a Prospective Clinical Study. Hidiatov O, Gaupp A, Marini I, Pelzl L, Wagner M, Rigoni F, Witzemann A, Häberle H, Martus P, Ngamsri KC, Konrad FM, Rosenberger P, Straub A, Bakchoul T, Althaus K.
Thromb Haemost. 2023 Apr;123(4):415-426. doi: 10.1055/a-1988-3174. Epub 2022 Nov 28.
PMID: 36442804

22.    Uterine allograft removal by total laparoscopic hysterectomy after successful cesarean delivery in a living-donor uterus recipient with uterovaginal agenesis (MRKHS).
Brucker SY, Krämer B, Abele H, Henes M, Hoopmann M, Schöller D, Königsrainer A, Bösmüller H, Nikolaou K, Krumm P, Rosenberger P, Heim E,
Amend B, Rausch S, Althaus K, Bakchoul T, Guthoff M, Heyne N, Nadalin S, Rall KK. 
Arch Gynecol Obstet. 2023 Mar;307(3):827-840. doi: 10.1007/s00404-022-06796-7. Epub 2022 Nov 7. 
PMID: 36342536 Free PMC article.  

23.     Phenotypic Characterization of EIF2AK4 Mutation Carriers in a Large Cohort
of Patients Diagnosed Clinically With Pulmonary Arterial Hypertension. Hadinnapola C, Bleda M, Haimel M, Screaton N, Swift A, Dorfmüller P, Preston SD, Southwood M, Hernandez-Sanchez J, Martin J, Treacy C, Yates K, Bogaard H, Church C, Coghlan G, Condliffe R, Corris PA, Gibbs S, Girerd B, Holden S, Humbert M, Kiely DG, Lawrie A, Machado R, MacKenzie Ross R, Moledina S, Montani D, Newnham M, Peacock A, Pepke-Zaba J, Rayner-Matthews P, Shamardina O, Soubrier F, Southgate L, Suntharalingam J, Toshner M, Trembath R, Vonk Noordegraaf A, Wilkins MR, Wort SJ, Wharton J; NIHR BioResource–Rare Diseases Consortium; UK National Cohort Study of Idiopathic and Heritable PAH; Gräf S, Morrell NW.
Circulation. 2017 Nov 21;136(21):2022-2033. doi:
10.1161/CIRCULATIONAHA.117.028351. Epub 2017 Sep 28.
PMID: 28972005 Free PMC article.
 

PubMed Results 2021

1.     The EHA Research Roadmap: Platelet Disorders. 
Balduini C, Freson K, Greinacher A, Gresele P, Kühne T, Scully M, Bakchoul T, Coppo P, Dovc Drnovsek T, Godeau B, Gruel Y, Rao AK, Kremer Hovinga JA, Makris M, Matzdorff A, Mumford A, Pecci A, Raslova H, Rivera J, Roberts I, Scharf RE, Semple JW, Van Geet C. 
Hemasphere. 2021 Jun 30;5(7):e601. doi: 10.1097/HS9.0000000000000601. eCollection 2021 Jul. 
PMID: 34476343 Free PMC article. No abstract available. 

2.    Accuracy of Diagnosing Heparin-Induced Thrombocytopenia.
Larsen EL, Nilius H, Studt JD, Tsakiris DA, Greinacher A, Mendez A, Schmidt A, Wuillemin WA, Gerber B, Vishnu P, Graf L, Kremer Hovinga JA, Goetze JP, Bakchoul T, Nagler M.
JAMA Netw Open. 2024 Mar 4;7(3):e243786. doi:
10.1001/jamanetworkopen.2024.3786.
PMID: 38530310 Free PMC article.

3.    Primary Immune Thrombocytopenia: Novel Insights into Pathophysiology and Disease Management.
Singh A, Uzun G, Bakchoul T.
J Clin Med. 2021 Feb 16;10(4):789. doi: 10.3390/jcm10040789.
PMID: 33669423 Free PMC article. Review.

4.    Inhaled prostacyclin therapy in the acute respiratory distress syndrome: a randomized controlled multicenter trial.
Haeberle HA, Calov S, Martus P, Serna-Higuita LM, Koeppen M, Goll A, Bernard A, Zarbock A, Meersch M, Weiss R, Mehrländer M, Marx G, Putensen C, Bakchoul T, Magunia H, Nieswandt B, Mirakaj V, Rosenberger P.
Respir Res. 2023 Feb 18;24(1):58. doi: 10.1186/s12931-023-02346-0.
PMID: 36805707 Free PMC article. Clinical Trial.

5.    New Developments in the Pathophysiology and Management of Primary Immune Thrombocytopenia.
Althaus K, Faul C, Bakchoul T.
Hamostaseologie. 2021 Aug;41(4):275-282. doi: 10.1055/a-1311-8264. Epub 2020 Dec 21.
PMID: 33348391 Review.

6.    Antibody-induced procoagulant platelets in severe COVID-19 infection. Althaus K, Marini I, Zlamal J, Pelzl L, Singh A, Häberle H, Mehrländer M, Hammer S, Schulze H, Bitzer M, Malek N, Rath D, Bösmüller H, Nieswandt B, Gawaz M, Bakchoul T, Rosenberger P.
Blood. 2021 Feb 25;137(8):1061-1071. doi: 10.1182/blood.2020008762. PMID: 33512415 Free PMC article.

7.    Cerebral venous sinus thrombosis due to vaccine-induced immune thrombotic thrombocytopenia in middle-income countries.
van de Munckhof A, Borhani-Haghighi A, Aaron S, Krzywicka K, van Kammen MS, Cordonnier C, Kleinig TJ, Field TS, Poli S, Lemmens R, Scutelnic A, Lindgren E, Duan J, Arslan Y, van Gorp EC, Kremer Hovinga JA, Günther A, Jood K, Tatlisumak T, Putaala J, Heldner MR, Arnold M, de Sousa DA, Wasay M, Arauz A, Conforto AB, Ferro JM, Coutinho JM; Cerebral Venous Sinus Thrombosis with Thrombocytopenia Syndrome Study Group.
Int J Stroke. 2023 Oct;18(9):1112-1120. doi: 10.1177/17474930231182901. Epub 2023 Jun 30.
PMID: 37277922 Free PMC article.

8.    Autoantibody-mediated desialylation impairs human thrombopoiesis and platelet lifespan.
Marini I, Zlamal J, Faul C, Holzer U, Hammer S, Pelzl L, Bethge W, Althaus K, Bakchoul T.
Haematologica. 2021 Jan 1;106(1):196-207. doi:
10.3324/haematol.2019.236117.
PMID: 31857361 Free PMC article.

9.    Antibody-mediated procoagulant platelet formation in COVID-19 is AKT dependent.
Pelzl L, Singh A, Funk J, Witzemann A, Marini I, Zlamal J, Weich K, Abou-Khalel W, Hammer S, Uzun G, Althaus K, Bakchoul T.
J Thromb Haemost. 2022 Feb;20(2):387-398. doi: 10.1111/jth.15587. Epub 2021 Dec 3.
PMID: 34752677 Free PMC article.

10.    Antibody-mediated procoagulant platelets in SARS-CoV-2-vaccination associated immune thrombotic thrombocytopenia.
Althaus K, Möller P, Uzun G, Singh A, Beck A, Bettag M, Bösmüller H, Guthoff M, Dorn F, Petzold GC, Henkes H, Heyne N, Jumaa H, Kreiser K, Limpach C, Luz B, Maschke M, Müller JA, Münch J, Nagel S, Pötzsch B, Müller J, Schlegel C, Viardot A, Bäzner H, Wolf M, Pelzl L, Warm V, Willinek WA, Steiner J, Schneiderhan-Marra N, Vollherbst D, Sachs UJ, Fend F, Bakchoul T. Haematologica. 2021 Aug 1;106(8):2170-2179. doi:
10.3324/haematol.2021.279000.
PMID: 34011137 Free PMC article.

11.    The use of IV immunoglobulin in the treatment of vaccine-induced immune thrombotic thrombocytopenia.
Uzun G, Althaus K, Singh A, Möller P, Ziemann U, Mengel A, Rosenberger P, Guthoff M, Petzold GC, Müller J, Büchsel M, Feil K, Henkes H, Heyne N, Maschke M, Limpach C, Nagel S, Sachs UJ, Fend F, Bakchoul T.
Blood. 2021 Sep 16;138(11):992-996. doi: 10.1182/blood.2021012479. PMID: 34166507 Free PMC article. No abstract available.

12.    No Correlation between Anti-PF4 and Anti-SARS-CoV-2 Antibodies after ChAdOx1 nCoV-19 Vaccination.
Uzun G, Althaus K, Bakchoul T.
N Engl J Med. 2021 Sep 30;385(14):1334-1336. doi: 10.1056/NEJMc2111305. Epub 2021 Aug 25.
PMID: 34432977 Free PMC article. No abstract available.

13.    SARS-CoV-2-derived peptides define heterologous and COVID-19-induced T cell recognition.
Nelde A, Bilich T, Heitmann JS, Maringer Y, Salih HR, Roerden M, Lübke M, Bauer J, Rieth J, Wacker M, Peter A, Hörber S, Traenkle B, Kaiser PD, Rothbauer U, Becker M, Junker D, Krause G, Strengert M, Schneiderhan-Marra N, Templin MF, Joos TO, Kowalewski DJ, Stos-Zweifel V, Fehr M, Rabsteyn A, Mirakaj V, Karbach J, Jäger E, Graf M, Gruber LC, Rachfalski D, Preuß B, Hagelstein I, Märklin M, Bakchoul T, Gouttefangeas C, Kohlbacher O, Klein R, Stevanović S, Rammensee HG, Walz JS.
Nat Immunol. 2021 Jan;22(1):74-85. doi: 10.1038/s41590-020-00808-x. Epub 2020 Sep 30.
PMID: 32999467

14.    Immune response to SARS-CoV-2 variants of concern in vaccinated individuals.
Becker M, Dulovic A, Junker D, Ruetalo N, Kaiser PD, Pinilla YT, Heinzel C, Haering J, Traenkle B, Wagner TR, Layer M, Mehrlaender M, Mirakaj V, Held J, Planatscher H, Schenke-Layland K, Krause G, Strengert M, Bakchoul T, Althaus K, Fendel R, Kreidenweiss A, Koeppen M, Rothbauer U, Schindler M, Schneiderhan-Marra N.
Nat Commun. 2021 May 25;12(1):3109. doi: 10.1038/s41467-021-23473-6. PMID: 34035301 Free PMC article.

15.    Antibody Response against SARS-CoV-2 and Seasonal Coronaviruses in Nonhospitalized COVID-19 Patients.
Ruetalo N, Businger R, Althaus K, Fink S, Ruoff F, Pogoda M, Iftner A, Ganzenmüller T, Hamprecht K, Flehmig B, Bakchoul T, Templin MF, Schindler M.
mSphere. 2021 Feb 24;6(1):e01145-20. doi: 10.1128/mSphere.01145-20. PMID: 33627511 Free PMC article.

16.    Proteinuric chronic kidney disease is associated with altered red blood cell lifespan, deformability and metabolism.
Bissinger R, Nemkov T, D'Alessandro A, Grau M, Dietz T, Bohnert BN, Essigke D, Wörn M, Schaefer L, Xiao M, Beirne JM, Kalo MZ, Schork A, Bakchoul T, Omage K, Kong L, Gonzalez-Menendez I, Quintanilla-Martinez L, Fehrenbacher B, Schaller M, Dhariwal A, Birkenfeld AL, Grahammer F, Qadri SM, Artunc F.

 

 PubMed Results 2020 

1.    Whole-genome sequencing of patients with rare diseases in a national health system.
Turro E, Astle WJ, Megy K, Gräf S, Greene D, Shamardina O, Allen HL, Sanchis-Juan A, Frontini M, Thys C, Stephens J, Mapeta R, Burren OS, Downes K, Haimel M, Tuna S, Deevi SVV, Aitman TJ, Bennett DL, Calleja P, Carss K, Caulfield MJ, Chinnery PF, Dixon PH, Gale DP, James R, Koziell A, Laffan MA, Levine AP, Maher ER, Markus HS, Morales J, Morrell NW, Mumford AD, Ormondroyd E, Rankin S, Rendon A, Richardson S, Roberts I, Roy NBA, Saleem MA, Smith KGC, Stark H, Tan RYY, Themistocleous AC, Thrasher AJ, Watkins H, Webster AR, Wilkins MR, Williamson C, Whitworth J, Humphray S, Bentley DR; NIHR BioResource for the 100,000 Genomes Project; Kingston N, Walker N, Bradley JR, Ashford S, Penkett CJ, Freson K, Stirrups KE, Raymond FL, Ouwehand WH.
Nature. 2020 Jul;583(7814):96-102. doi: 10.1038/s41586-020-2434-2. Epub 2020 Jun 24.
PMID: 32581362 Free PMC article.

2.    Whole-genome sequencing of a sporadic primary immunodeficiency cohort. Thaventhiran JED, Lango Allen H, Burren OS, Rae W, Greene D, Staples E, Zhang Z, Farmery JHR, Simeoni I, Rivers E, Maimaris J, Penkett CJ, Stephens J, Deevi SVV, Sanchis-Juan A, Gleadall NS, Thomas MJ, Sargur RB, Gordins P, Baxendale HE, Brown M, Tuijnenburg P, Worth A, Hanson S, Linger RJ, Buckland MS, Rayner-Matthews PJ, Gilmour KC, Samarghitean C, Seneviratne SL, Sansom DM, Lynch AG, Megy K, Ellinghaus E, Ellinghaus D, Jorgensen SF, Karlsen TH, Stirrups KE, Cutler AJ, Kumararatne DS, Chandra A, Edgar JDM, Herwadkar A, Cooper N, Grigoriadou S, Huissoon AP, Goddard S, Jolles S, Schuetz C, Boschann F; Primary Immunodeficiency Consortium for the NIHR Bioresource; Lyons PA, Hurles ME, Savic S, Burns SO, Kuijpers TW, Turro E, Ouwehand WH, Thrasher AJ, Smith KGC.
Nature. 2020 Jul;583(7814):90-95. doi: 10.1038/s41586-020-2265-1. Epub 2020 May 6.
PMID: 32499645 Free PMC article.

3.    Effects of Liberal vs Restrictive Transfusion Thresholds on Survival and Neurocognitive Outcomes in Extremely Low-Birth-Weight Infants: The ETTNO Randomized Clinical Trial.
Franz AR, Engel C, Bassler D, Rüdiger M, Thome UH, Maier RF, Krägeloh-Mann I, Kron M, Essers J, Bührer C, Rellensmann G, Rossi R, Bittrich HJ, Roll C, Höhn T, Ehrhardt H, Avenarius S, Körner HT, Stein A, Buxmann H, Vochem M, Poets CF; ETTNO Investigators.
JAMA. 2020 Aug 11;324(6):560-570. doi: 10.1001/jama.2020.10690.
PMID: 32780138 Free PMC article. Clinical Trial.

4.    Proteomic profiling for biomarker discovery in heparin-induced thrombocytopenia.
Nilius H, Hamzeh-Cognasse H, Hastings J, Studt JD, Tsakiris DA, Greinacher A, Mendez A, Schmidt A, Wuillemin WA, Gerber B, Vishnu P, Graf L, Kremer Hovinga JA, Bakchoul T, Cognasse F, Nagler M. 
Blood Adv. 2024 Jun 11;8(11):2825-2834. doi: 
10.1182/bloodadvances.2024012782. 
PMID: 38588487 Free PMC article.  

5.    New Developments in the Pathophysiology and Management of Primary Immune Thrombocytopenia.
Althaus K, Faul C, Bakchoul T.
Hamostaseologie. 2021 Aug;41(4):275-282. doi: 10.1055/a-1311-8264. Epub 2020 Dec 21.
PMID: 33348391 Review.

6.    SARS-CoV-2-derived peptides define heterologous and COVID-19-induced T cell recognition.
Nelde A, Bilich T, Heitmann JS, Maringer Y, Salih HR, Roerden M, Lübke M, Bauer J, Rieth J, Wacker M, Peter A, Hörber S, Traenkle B, Kaiser PD, Rothbauer U, Becker M, Junker D, Krause G, Strengert M, Schneiderhan-Marra N, Templin MF, Joos TO, Kowalewski DJ, Stos-Zweifel V, Fehr M, Rabsteyn A, Mirakaj V, Karbach J, Jäger E, Graf M, Gruber LC, Rachfalski D, Preuß B, Hagelstein I, Märklin M, Bakchoul T, Gouttefangeas C, Kohlbacher O, Klein R, Stevanović S, Rammensee HG, Walz JS.
Nat Immunol. 2021 Jan;22(1):74-85. doi: 10.1038/s41590-020-00808-x. Epub 2020 Sep 30.
PMID: 32999467

7.    Immune response to SARS-CoV-2 variants of concern in vaccinated individuals.
Becker M, Dulovic A, Junker D, Ruetalo N, Kaiser PD, Pinilla YT, Heinzel C, Haering J, Traenkle B, Wagner TR, Layer M, Mehrlaender M, Mirakaj V, Held J, Planatscher H, Schenke-Layland K, Krause G, Strengert M, Bakchoul T, Althaus K, Fendel R, Kreidenweiss A, Koeppen M, Rothbauer U, Schindler M, Schneiderhan-Marra N.
Nat Commun. 2021 May 25;12(1):3109. doi: 10.1038/s41467-021-23473-6. PMID: 34035301 Free PMC article.

8.    Beta-Glycerophosphate-Induced ORAI1 Expression and Store Operated Ca2+ Entry in Megakaryocytes.
Pelzl L, Sahu I, Ma K, Heinzmann D, Bhuyan AAM, Al-Maghout T, Sukkar B, Sharma Y, Marini I, Rigoni F, Artunc F, Cao H, Gutti R, Voelkl J, Pieske B, Gawaz M, Bakchoul T, Lang F.
Sci Rep. 2020 Feb 3;10(1):1728. doi: 10.1038/s41598-020-58384-x.
PMID: 32015442 Free PMC article.

9.    Real-life evaluation of an automated immunoassay for diagnosis of heparin-induced thrombocytopenia.
Althaus K, Westphal A, Strobel U, Bakchoul T, Greinacher A. 
Thromb Res. 2020 Dec;196:400-403. doi: 10.1016/j.thromres.2020.09.032. Epub 2020 Sep 25. 
PMID: 33010528 No abstract available. 

10.    Red blood cell-derived semaphorin 7A promotes thrombo-inflammation in myocardial ischemia-reperfusion injury through platelet GPIb.
Köhler D, Granja T, Volz J, Koeppen M, Langer HF, Hansmann G, Legchenko E, Geisler T, Bakchoul T, Eggstein C, Häberle HA, Nieswandt B, Rosenberger P. Nat Commun. 2020 Mar 11;11(1):1315. doi: 10.1038/s41467-020-14958-x. PMID: 32161256 Free PMC article.

11.    Blood donor-derived buffy coat to produce platelets in vitro.
Marini I, Rigoni F, Zlamal J, Pelzl L, Althaus K, Nowak-Harnau S, Rondina MT, Bakchoul T.
Vox Sang. 2020 Jan;115(1):94-102. doi: 10.1111/vox.12863. Epub 2019 Nov 10.
PMID: 31709567

12.    Fetal/neonatal alloimmune thrombocytopenia: a systematic review of impact of HLA-DRB3*01:01 on fetal/neonatal outcome.
12.    Kjeldsen-Kragh J, Fergusson DA, Kjaer M, Lieberman L, Greinacher A, Murphy MF, Bussel J, Bakchoul T, Corke S, Bertrand G, Oepkes D, Baker JM, Hume H, Massey E, Kaplan C, Arnold DM, Baidya S, Ryan G, Savoia HF, Landry D, Shehata N.
Blood Adv. 2020 Jul 28;4(14):3368-3377. doi:
10.1182/bloodadvances.2020002137.
PMID: 32717028 Free PMC article.

13.    Heparin-induced thrombocytopenia: Diagnostic challenges in intensive care patients especially with extracorporeal circulation.
Althaus K, Straub A, Häberle H, Rosenberger P, Hidiatov O, Hammer S, Nowak-Harnau S, Enkel S, Riessen R, Bakchoul T.
Thromb Res. 2020 Apr;188:52-60. doi: 10.1016/j.thromres.2020.01.026. Epub 2020 Jan 29.
PMID: 32059134

14.    Low-dose alemtuzumab induction in a tailored immunosuppression protocol for sensitized kidney transplant recipients.
Guthoff M, Berger K, Althaus K, Mühlbacher T, Bakchoul T, Steurer W, Nadalin S, Königsrainer A, Heyne N.
BMC Nephrol. 2020 May 13;21(1):178. doi: 10.1186/s12882-020-01767-z. PMID: 32404066 Free PMC article.

15.    One-year follow-up of the CAPSID randomized trial for high-dose convalescent plasma in severe COVID-19 patients.
Körper S, Grüner B, Zickler D, Wiesmann T, Wuchter P, Blasczyk R, Zacharowski K, Spieth P, Tonn T, Rosenberger P, Paul G, Pilch J, Schwäble J,
Bakchoul T, Thiele T, Knörlein J, Dollinger MM, Krebs J, Bentz M, Corman VM, Kilalic D, Schmidtke-Schrezenmeier G, Lepper PM, Ernst L, Wulf H, Ulrich A, Weiss M, Kruse JM, Burkhardt T, Müller R, Klüter H, Schmidt M, Jahrsdörfer B, Lotfi R, Rojewski M, Appl T, Mayer B, Schnecko P, Seifried E, Schrezenmeier H. 
J Clin Invest. 2022 Dec 15;132(24):e163657. doi: 10.1172/JCI163657. 
PMID: 36326824 Free PMC article. Clinical Trial.  

16.    Publisher Correction: Whole-genome sequencing of a sporadic primary immunodeficiency cohort.
Thaventhiran JED, Lango Allen H, Burren OS, Rae W, Greene D, Staples E, Zhang Z, Farmery JHR, Simeoni I, Rivers E, Maimaris J, Penkett CJ, Stephens J, Deevi SVV, Sanchis-Juan A, Gleadall NS, Thomas MJ, Sargur RB, Gordins P, Baxendale HE, Brown M, Tuijnenburg P, Worth A, Hanson S, Linger RJ, Buckland MS, Rayner-Matthews PJ, Gilmour KC, Samarghitean C, Seneviratne SL, Sansom DM, Lynch AG, Megy K, Ellinghaus E, Ellinghaus D, Jorgensen SF, Karlsen TH, Stirrups KE, Cutler AJ, Kumararatne DS, Chandra A, Edgar JDM, Herwadkar A, Cooper N, Grigoriadou S, Huissoon AP, Goddard S, Jolles S, Schuetz C, Boschann F; Primary Immunodeficiency Consortium for the NIHR Bioresource; Lyons PA, Hurles ME, Savic S, Burns SO, Kuijpers TW, Turro E, Ouwehand WH, Thrasher AJ, Smith KGC.
Nature. 2020 Aug;584(7819):E2. doi: 10.1038/s41586-020-2556-6.
PMID: 32678341

17.    [Acquired immune thrombocytopenia: An update on aspects of diagnosis and management relevant for intensive care medicine].
Hidiatov O, Zlamal J, Aidery P, Bakchoul T.
Dtsch Med Wochenschr. 2020 Jun;145(11):747-753. doi: 10.1055/a-0962-6361. Epub 2020 Jun 3.
PMID: 32492744 German.

18.    Flow Cytometric Assessment of AKT Signaling in Platelet Activation: An Alternative Diagnostic Tool for Small Volumes of Blood.
Althaus K, Wagner M, Marini I, Bakchoul T, Pelzl L.
Hamostaseologie. 2020 Nov;40(S 01):S21-S25. doi: 10.1055/a-1282-1989. Epub 2020 Nov 13.
PMID: 33187007

19.    IGLV3-21*01 is an inherited risk factor for CLL through the acquisition of a single-point mutation enabling autonomous BCR signaling.
Maity PC, Bilal M, Koning MT, Young M, van Bergen CAM, Renna V, Nicolò A, Datta M, Gentner-Göbel E, Barendse RS, Somers SF, de Groen RAL, Vermaat JSP, Steinbrecher D, Schneider C, Tausch E, Bittolo T, Bomben R, Mazzarello AN, Del Poeta G, Kroes WGM, van Wezel JT, Imkeller K, Busse CE, Degano M, Bakchoul T, Schulz AR, Mei H, Ghia P, Kotta K, Stamatopoulos K, Wardemann H, Zucchetto A, Chiorazzi N, Gattei V, Stilgenbauer S, Veelken H, Jumaa H.
Proc Natl Acad Sci U S A. 2020 Feb 25;117(8):4320-4327. doi: 10.1073/pnas.1913810117. Epub 2020 Feb 11. 
PMID: 32047037 Free PMC article.  

20.    Living-Donor Uterus Transplantation: Pre-, Intra-, and Postoperative Parameters Relevant to Surgical Success, Pregnancy, and Obstetrics with Live Births.
Brucker SY, Strowitzki T, Taran FA, Rall K, Schöller D, Hoopmann M, Henes M, Guthoff M, Heyne N, Zipfel S, Schäffeler N, Bösmüller H, Fend F, Rosenberger P, Heim E, Wiesing U, Nikolaou K, Fleischer S, Bakchoul T, Poets CF, Goelz R, Wiechers C, Kagan KO, Krämer B, Reisenauer C, Oberlechner E, Hübner S, Abele H, Dahm-Kähler P, Kvarnström N, Brännström M, Nadalin S, Wallwiener D, Königsrainer A.
J Clin Med. 2020 Aug 3;9(8):2485. doi: 10.3390/jcm9082485.
PMID: 32756295 Free PMC article.

21.    Feasibility of precise and reliable glucose quantification in human whole blood samples by 1 tesla benchtop NMR.
Stolz M, Schlawne C, Hoffmann J, Hartmann V, Marini I, Fritsche A, Peter A, Bakchoul T, Schick F.
NMR Biomed. 2020 Sep;33(9):e4358. doi: 10.1002/nbm.4358. Epub 2020 Jul 2.
PMID: 32618045

22.    Characteristics Associated with COVID-19 Breakthrough Infections after Booster Vaccinations in Healthcare Workers: Insights from the TüSeRe:exact Study.
Uzun G, Bareiß A, Becker M, Althaus K, Dulovic A, Junker D, Schenke-Layland K, Martus P, Borst O, Schneiderhan-Marra N, Bakchoul T.
J Clin Med. 2024 Mar 9;13(6):1571. doi: 10.3390/jcm13061571.
PMID: 38541797 Free PMC article.

23.    Defibrotide for the Treatment of Pediatric Inflammatory Multisystem Syndrome Temporally Associated With Severe Acute Respiratory Syndrome Coronavirus 2 Infection in 2 Pediatric Patients.
Lang P, Eichholz T, Bakchoul T, Streiter M, Petrasch M, Bösmüller H, Klein R, Rabsteyn A, Lang AM, Adams C, Klingel K, Gessner M, Rosenberger P, Ruef P, Handgretinger R.
J Pediatric Infect Dis Soc. 2020 Nov 10;9(5):622-625. doi:
10.1093/jpids/piaa117.
PMID: 32951037 Free PMC article.

24.     Platelet dysfunction caused by a novel thromboxane A2 receptor mutation and congenital thrombocytopenia in a case of mild bleeding.
Bugert P, Fischer L, Althaus K, Knöfler R, Bakchoul T.
Platelets. 2020;31(2):276-279. doi: 10.1080/09537104.2019.1652264. Epub 2019 Aug 7.
PMID: 31389738

25.     Fibrinolysis shut down in COVID-19 patients: Report on two severe cases with potential diagnostic and clinical relevance.
Bakchoul T, Hammer S, Lang P, Rosenberger P.
Thromb Update. 2020 Dec;1:100008. doi: 10.1016/j.tru.2020.100008. Epub 2020 Aug 26.
PMID: 38620653 Free PMC article.

 

• Marini I, Rigoni F, Zlamal J, Pelzl L, Althaus K, Nowak-Harnau S, Rondina MT, Bakchoul T. Blood donor-derived buffy coat to produce platelets in vitro. Vox Sang. 2019 Nov

 Baker JM, Shehata N, Bussel J, Murphy MF, Greinacher A, Bakchoul T, Massey E, Lieberman L, Landry D, Tanael S, Arnold DM, Baidya S, Bertrand G, Kjaer M, Kaplan C, Kjeldsen-Kragh J, Oepkes D, Savoia H, Ryan G, Hume H. Postnatal intervention for the treatment of FNAIT: a systematic review.J Perinatol. 2019 Oct.

• Bury L, Megy K, Stephens JC, Grassi L, Greene D, Gleadall N, Althaus K, Allsup D, Bariana TK, Bonduel M, Butta NV, Collins P, Curry N, Deevi SVV, Downes K, Duarte D, Elliott K, Falcinelli E, Furie B, Keeling D, Lambert MP, Linger R, Mangles S, Mapeta R, Millar CM, Penkett C, Perry DJ, Stirrups KE, Turro E, Westbury SK, Wu J, BioResource N, Gomez K, Freson K, Ouwehand WH, Gresele P, Simeoni I. Next-generation sequencing for the diagnosis of MYH9-RD: Predicting pathogenic variants. Hum Mutat. 2019 Sep

• Bakchoul T. Immune Thrombocytopenia-A Disease or a Group of Disorders? Where Do We Stand in 2019? Hamostaseologie. 2019 Aug

• Bugert P, Fischer L, Althaus K, Knöfler R, Bakchoul T. Platelet dysfunction caused by a novel thromboxane A2 receptor mutation and congenital thrombocytopenia in a case of mild bleeding. Platelets. 2019 Aug

• Marini I, Bakchoul T. Pathophysiology of Autoimmune Thrombocytopenia: Current Insight with a Focus on Thrombopoiesis. Hamostaseologie. 2019 Aug

• Althaus K, Pelzl L, Hidiatov O, Amiral J, Marini I and Bakchoul T. Evaluation of a flow cytometer-based functional assay using platelet-rich plasma in the diagnosis of heparin-induced thrombocytopenia. Thrombosis Research, 2019 Aug

• Ziemann M, Altermann W, Angert K, Arns W, Bachmann A, Bakchoul T, Banas B, von Borstel A, Budde K, Ditt V, Einecke G, Eisenberger U, Feldkamp T, Görg S, Guthoff M, Habicht A, Hallensleben M, Heinemann FM, Hessler N, Hugo C, Kaufmann M, Kauke T, Koch M, König IR, Kurschat C, Lehmann C, Marget M, Mühlfeld A, Nitschke M, Pego da Silva L, Quick C, Rahmel A, Rath T, Reinke P, Renders L, Sommer F, Spriewald B, Staeck O, Stippel D, Süsal C, Thiele B, Zecher D, Lachmann N. Preformed Donor-Specific HLA Antibodies in Living and Deceased Donor Transplantation: A Multicenter Study. Clin J Am Soc Nephrol. 2019 Jul 5

• Althaus, K. et al. Diagnose der Thrombozytenfunktionsstörungen Transfusionsmedizin 2019; 9:96 -108

• Althaus K, Zieger B, Bakchoul T, Jurk K. Standardization of Light Transmission Aggregometry for Diagnosis of Platelet Disorders: An Inter-Laboratory External Quality Assessment. Thromb Haemost. 2019 Jul.

• Bakchoul T, Borst O, Riessen R, Lucic J, Gawaz M, Althaus K, Aidery P. Autoimmune Heparin-Induced Thrombocytopenia after Transcatheter Aortic Valve Implantation: Successful Treatment with Adjunct High-Dose Intravenous Immunoglobulin. TH Open. 2019 Jun

• Werner S, Krauss B, Haberland U, Bongers M, Starke U, Bakchoul T, Enkel S, Nikolaou K, Horger M. Dual-energy CT for liver iron quantification in patients with haematological disorders. Eur Radiol. 2019 Jun

• Vollenberg R, Jouni R, Norris PAA, Burg-Roderfeld M, Cooper N, Rummel MJ, Bein G, Marini I, Bayat B, Burack R, Lazarus AH, Bakchoul T, Sachs UJ. Glycoprotein V is a relevant immune target in patients with immune thrombocytopenia. Haematologica. 2019 Jun

• Lieberman L, Greinacher A, Murphy MF, Bussel J, Bakchoul T, Corke S, Kjaer M, Kjeldsen-Kragh J, Bertrand G, Oepkes D, Baker JM, Hume H, Massey E, Kaplan C, Arnold DM, Baidya S, Ryan G, Savoia H, Landry D, Shehata N. Fetal and neonatal alloimmune thrombocytopenia: recommendations for evidence-based practice, an international approach. Br J Haematol. 2019 May.

• Baker JM, Shehata N, Bussel J, Murphy MF, Greinacher A, Bakchoul T, Massey E, Lieberman L, Landry D, Tanael S, Arnold DM, Baidya S, Bertrand G, Kjaer M, Kaplan C, Kjeldsen-Kragh J, Oepkes D, Savoia H, Ryan G, Hume H. Postnatal intervention for the treatment of FNAIT: a systematic review.J Perinatol. 2019 Apr 10.

• Eekels JJM, Althaus K, Bakchoul T, Kroll H, Kiefel V, Nazy I, Lee LS, Sachs UJ, Warkentin TE, Greinacher A. An international External Quality Assessment for laboratory diagnosis of Heparin-Induced Thrombocytopenia. J Thromb Haemost. 2019 Mar

• Marini I, Bakchoul T. Pathophysiology of Autoimmune Thrombocytopenia: Current Insight with a Focus on Thrombopoiesis. Hamostaseologie. 2019 Feb 25.

• Kjaer M, Bertrand G, Bakchoul T, Massey E, Baker JM, Lieberman L, Tanael S, Greinacher A, Murphy MF, Arnold DM, Baidya S, Bussel J, Hume H, Kaplan C, Oepkes D, Ryan G, Savoia H, Shehata N, Kjeldsen-Kragh J; International Collaboration for Transfusion Medicine Guidelines. Maternal HPA-1a antibody level and its role in predicting the severity of Fetal/Neonatal Alloimmune Thrombocytopenia: a systematic review. Vox Sang. 2019 Jan

Vollenberg R, Jouni R, Norris PAA, Burg-Roderfeld M, Cooper N, Rummel MJ, Bein G, Marini I, Bayat B, Burack R, Lazarus AH, Bakchoul T, Sachs UJ. Glycoprotein V is a relevant immune target in patients with immune thrombocytopenia. Haematologica. 2019 Mar 28. pii: haematol.2018.211086. doi: 10.3324/haematol.2018.211086. PMID: 30923095.

Althaus K, Pelzl L, Hidiatov O, Amiral J, Marini I and Bakchoul T. Evaluation of a flow cytometer-based functional assay using platelet-rich plasma in the diagnosis of heparin-induced thrombocytopenia. Thrombosis Research, in press.

Eekels JJM, Althaus K, Bakchoul T, Kroll H, Kiefel V, Nazy I, Lee LS, Sachs UJ, Warkentin TE, Greinacher A. An international External Quality Assessment for laboratory diagnosis of Heparin-Induced Thrombocytopenia. J Thromb Haemost. 2019 Jan 14. doi: 10.1111/jth.14383. [Epub ahead of print]

Taran FA, Schöller D, Rall K, Nadalin S, Königsrainer A, Henes M, Bösmüller H, Fend F, Nikolaou K, Notohamiprodjo M, Grasshoff C, Heim E, Zipfel S, Schäffeler N, Bakchoul T, Heyne N, Guthoff M, Krämer B, Reisenauer C, Hoopmann M, Kagan KO, Brännström M, Wallwiener D, Brucker SY. Screening and evaluation of potential recipients and donors for living donor uterus transplantation: results from a single-center observational study. Fertil Steril. 2019 Jan;111(1):186-193. doi: 10.1016/j.fertnstert.2018.09.010.

Andres O, König EM, Althaus K, Bakchoul T, Bugert P, Eber S, Knöfler R, Kunstmann E, Manukjan G, Meyer O, Strauß G, Streif W, Thiele T, Wiegering V, Klopocki E, Schulze H. Use of Targeted High-Throughput Sequencing for Genetic Classification of Patients with Bleeding Diathesis and Suspected Platelet Disorder. TH Open. 2018 Dec 30.

Strunk D, Lozano M, Marks DC, Loh YS, Gstraunthaler G, Schennach H, Rohde E, Laner-Plamberger S, Oller M, Nystedt J, Lotfi R, Rojewski M, Schrezenmeier H, Bieback K, Schafer R, Bakchoul T, Waidmann M, Jonsdottir-Buch SM, Montazeri H, Sigurjonsson OE, Iudicone P, Fioravanti D, Pierelli L, Introna M, Capelli C, Falanga A, Takanashi M, Lopez-Villar O, Burnouf T, Reems JA, Pierce J, Preslar AM, Schallmoser K. International Forum on GMP-grade human platelet lysate for cell propagation. Vox sanguinis. 2018;113(1):e1-e25.

• Strunk D, Lozano M, Marks DC, Loh YS, Gstraunthaler G, Schennach H, Rohde E, Laner-Plamberger S, Oller M, Nystedt J, Lotfi R, Rojewski M, Schrezenmeier H, Bieback K, Schafer R, Bakchoul T, Waidmann M, Jonsdottir-Buch SM, Montazeri H, Sigurjonsson OE, Iudicone P, Fioravanti D, Pierelli L, Introna M, Capelli C, Falanga A, Takanashi M, Lomicronpez-Villar O, Burnouf T, Reems JA, Pierce J, Preslar AM, Schallmoser K. International Forum on GMP-grade human platelet lysate for cell propagation: summary. Vox sanguinis. 2018;113(1):80-7.

Marini I, Aurich K, Jouni R, Nowak-Harnau S, Hartwich O, Greinacher A, Thiele T, Bakchoul T. Cold storage of platelets in additive solution: The impact of residual plasma in apheresis platelet concentrates. Haematologica. 2018.

• Taran F, Schöller D, Königsrainer A, Fend F, Nikolaou K, Rosenberger P, Bakchoul T, Heyne P, Wallwiener D, Brucker S. Screening and evaluation of potential recipients and living donors for uterus transplantation: results from an observational study. Fertility accepted 2018.

Petermann R, Bakchoul T, Curtis B, Miyata S, Arnold D. Investigations for fetal and neonatal alloimmune thrombocytopenia: communication from the SSC of the ISTH. Journal of Thrombosis and Haemostasis, 2018, 16: 1–4.

Werner S, Pichler P, Enkel S, Bakchoul T, Horger. Dual-energy CT for liver iron quantification in patients with haematological disorders. European Radiology 2018 accepted. • Bakchoul T, Marini I. Drug-associated thrombocytopenia. Hematology 2018. Accepted.

• Bakchoul T, Marini I. Drug-associated thrombocytopenia. Hematology 2018.

Zlamal J, Bakchoul T. Acquired immune thrombocytopenia: An update on pathophysiology, diagnosis and management. Annals of Blood 2018. Accepted.

• Marini I, Althaus K, Bakchoul T. Ex vivo Thrombopoese: Könnte das Blutplättchen im Labor produziert werden? Hämotherapie 29/2018.

Marini I, Bakchoul T. Pathophysiology of autoimmune thrombocytopenia: Current insight with a focus on thrombopoiesis. Hämostaseologie 2018. Accepted.

Kjaer M, Bertrand G, Bakchoul T, Massey E, Baker JM, Lieberman L, Tanael S, Greinacher A, Murphy MF, Arnold DM, Baidya S, Bussel J, Hume H, Kaplan C, Oepkes D, Ryan G, Savoia H, Shehata N, Kjeldsen-Kragh J; Maternal HPA-1a antibody level and its role in predicting the severity of Fetal/Neonatal Alloimmune Thrombocytopenia: a systematic review. Vox Sang. 2018 Nov 22. doi: 10.1111/vox.12725. [Epub ahead of print]

Siegel G, Fleck E, Elser S, Hermanutz-Klein U, Waidmann M, Northoff H, Seifried E, Schäfer R. Manufacture of endothelial colony-forming progenitor cells from steady-state peripheral blood leukapheresis using pooled human platelet lysate. Transfusion. 2018 May;58(5):1132-1142. doi: 10.1111/trf.14541. Epub 2018 Feb 22.

Bariana TK, Labarque V, Heremans J, Thys C, De Reys M, Greene D, Jenkins B, Grassi L, Seyres D, Burden F, Whitehorn D, Shamardina O, Papadia S, Gomez K; NIHR BioResource, Van Geet C, Koulman A, Ouwehand WH, Ghevaert C, Frontini M, Turro E, Freson K. Sphingolipid dysregulation due to lack of functional KDSR impairs proplatelet formation causing thrombocytopenia. Haematologica. 2018 Nov 22. pii: haematol.2018.204784. doi: 10.3324/haematol.2018.204784. [Epub ahead of print]

Revel-Vilk S, Shai E, Turro E, Jahshan N, Hi-Am E, Spectre G, Daum H, Kalish Y, Althaus K, Greinacher A, Kaplinsky C, Izraeli S, Mapeta R, Deevi SVV, Jarocha D, Ouwehand WH, Downes K, Poncz M, Varon D, Lambert MP. GNE variants causing autosomal recessive macrothrombocytopenia without associated muscle wasting. Blood. 2018 Oct 25;132(17):1851-1854. doi: 10.1182/blood-2018-04-845545. Epub 2018 Aug 31. PubMed PMID: 30171045; PubMed Central PMCID: PMC6202914.

• Marini I, Athaus K, Bakchoul T. Ex vivo Thrombopoiese: Könnten Blutplättchen im Labor produziert werden?. Hämotherapie 30/2018.

Siegel G, Fleck E, Elser S, Hermanutz-Klein U, Waidmann M, Northoff H, Seifried E, Schäfer R. Manufacture of endothelial colony-forming progenitor cells from steady-state peripheral blood leukapheresis using pooled human platelet lysate Transfusion. 2018 May;58(5):1132-1142. doi: 10.1111/trf.14541. Epub 2018 Feb 22.

Zollner H, Jouni R, Panzer S, Khadour A, Janzen L, Wesche J, Ten Berg M, Schellong S, Heinken A, Greinacher A, Bakchoul T. Platelet activation in the presence of neutral protamine Hagedorn insulin: a new feature of antibodies against protamine/heparin complexes. Journal of thrombosis and haemostasis : JTH. 2017;15(1):176-84.

Bakchoul T, Wanner Y, Nowak-Harnau S. Heparininduzierte Thrombozytopenie: Ein Update über die Anwendung von direkten oralen Antikoagulanzien. Z GfäßMed 2017;14(4-9).

• Bakchoul T, Hinz A. Diagnostik von angeborenen und erworbenen Thrombozyten-Erkrankungen. Hämotherapie 28/2017.

Winkelhorst D, Murphy MF, Greinacher A, Shehata N, Bakchoul T, Massey E, Baker J, Lieberman L, Tanael S, Hume H, Arnold DM, Baidya S, Bertrand G, Bussel J, Kjaer M, Kaplan C, Kjeldsen-Kragh J, Oepkes D, Ryan G. Antenatal management in fetal and neonatal alloimmune thrombocytopenia: a systematic review. Blood. 2017;129(11):1538-47.

Schulze H, Schlagenhauf A, Manukjan G, Beham-Schmid C, Andres O, Klopocki E, Konig EM, Haidl H, Panzer S, Althaus K, Muntean WE, Schwinger W, Urban C, Greinacher A, Bakchoul T, Seidel MG. Recessive grey platelet-like syndrome with unaffected erythropoiesis in the absence of the splice isoform GFI1B-p37. Haematologica. 2017;102(9):e375-e8.

Greinacher A, Pecci A, Kunishima S, Althaus K, Nurden P, Balduini CL, Bakchoul T. Diagnosis of inherited platelet disorders on a blood smear: a tool to facilitate worldwide diagnosis of platelet disorders. Journal of thrombosis and haemostasis : JTH. 2017;15(7):1511-21.

Farm M, Bakchoul T, Frisk T, Althaus K, Odenrick A, Norberg EM, Berndtsson M, Antovic JP. Evaluation of a diagnostic algorithm for Heparin-Induced Thrombocytopenia. Thrombosis research. 2017;152:77-81.

Aurich K, Wesche J, Palankar R, Schluter R, Bakchoul T, Greinacher A. Magnetic Nanoparticle Labeling of Human Platelets from Platelet Concentrates for Recovery and Survival Studies. ACS Appl Mater Interfaces. 2017;9(40):34666-73.

• Platelet Lysate: The Better Choice for Jaw Periosteal Cell Mineralization. Wanner Y, Umrath F, Waidmann M, Reinert S, Alexander D. Stem Cells Int. 2017;2017:8303959. doi: 10.1155/2017/8303959. Epub 2017 Dec 17.

• Farm M, Bakchoul T, Frisk T, Althaus K, Odenrick A, Norberg EM, Berndtsson M, Antovic JP. Evaluation of a diagnostic algorithm for Heparin-Induced Thrombocytopenia. Thromb Res. 2017 Apr;152:77-81. doi:10.1016/j.thromres.2017.02.015. Epub 2017 Feb 24. PubMed PMID: 28262567.

Marini I, Siegemund M, Hutt M, Kontermann RE, Pfizenmaier K. Antitumor Activity of a Mesenchymal Stem Cell Line Stably Secreting a Tumor-Targeted TNF-Related Apoptosis-Inducing Ligand Fusion Protein..Front Immunol. 2017 May 11;8:536. doi: 10.3389/fimmu.2017.00536. eCollection 2017.PMID:28553285

Wanner Y, Umrath F, Waidmann M, Reinert S, Alexander D. Platelet Lysate: The Better Choice for Jaw Periosteal Cell Mineralization. Stem Cells Int. 2017;2017:8303959. doi: 10.1155/2017/8303959. Epub 2017 Dec 17.

Turro E, Greene D, Wijgaerts A, Thys C, Lentaigne C, Bariana TK, Westbury SK, Kelly AM, Selleslag D, Stephens JC, Papadia S, Simeoni I, Penkett CJ, Ashford S, Attwood A, Austin S, Bakchoul T, Collins P, Deevi SV, Favier R, Kostadima M, Lambert MP, Mathias M, Millar CM, Peerlinck K, Perry DJ, Schulman S, Whitehorn D, Wittevrongel C, Consortium B-B, De Maeyer M, Rendon A, Gomez K, Erber WN, Mumford AD, Nurden P, Stirrups K, Bradley JR, Raymond FL, Laffan MA, Van Geet C, Richardson S, Freson K, Ouwehand WH. A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies. Sci Transl Med. 2016;8(328):328ra30.

Stritt S, Nurden P, Turro E, Greene D, Jansen SB, Westbury SK, Petersen R, Astle WJ, Marlin S, Bariana TK, Kostadima M, Lentaigne C, Maiwald S, Papadia S, Kelly AM, Stephens JC, Penkett CJ, Ashford S, Tuna S, Austin S, Bakchoul T, Collins P, Favier R, Lambert MP, Mathias M, Millar CM, Mapeta R, Perry DJ, Schulman S, Simeoni I, Thys C, Consortium B-B, Gomez K, Erber WN, Stirrups K, Rendon A, Bradley JR, van Geet C, Raymond FL, Laffan MA, Nurden AT, Nieswandt B, Richardson S, Freson K, Ouwehand WH, Mumford AD. A gain-of-function variant in DIAPH1 causes dominant macrothrombocytopenia and hearing loss. Blood. 2016;127(23):2903-14.

Santoso S, Wihadmadyatami H, Bakchoul T, Werth S, Al-Fakhri N, Bein G, Kiefel V, Zhu J, Newman PJ, Bayat B, Sachs UJ. Antiendothelial alphavbeta3 Antibodies Are a Major Cause of Intracranial Bleeding in Fetal/Neonatal Alloimmune Thrombocytopenia. Arterioscler Thromb Vasc Biol. 2016;36(8):1517-24.

• Nagler M, Bakchoul T. Clinical and laboratory tests for the diagnosis of heparin-induced thrombocytopenia. Thrombosis and haemostasis. 2016;116(5):823-34.

Morel-Kopp MC, Mullier F, Gkalea V, Bakchoul T, Minet V, Elalamy I, Ward CM, subcommittee on platelet i. Heparin-induced multi-electrode aggregometry method for heparin-induced thrombocytopenia testing: communication from the SSC of the ISTH. Journal of thrombosis and haemostasis : JTH. 2016;14(12):2548-52.

Krauel K, Schulze A, Jouni R, Hackbarth C, Hietkamp B, Selleng S, Koster A, Jensch I, van der Linde J, Schwertz H, Bakchoul T, Hundt M, Greinacher A. Further insights into the anti-PF4/heparin IgM immune response. Thrombosis and haemostasis. 2016;115(4):752-61.

Jouni R, Zollner H, Khadour A, Wesche J, Grotevendt A, Brandt S, Delcea M, Krauel K, Schwertz H, Sachs UJ, Greinacher A, Bakchoul T. Partially desulfated heparin modulates the interaction between anti-protamine/heparin antibodies and platelets. Thrombosis and haemostasis. 2016;115(2):324-32.

Jatzlauk G, Althaus K, Strobel U, Kiefel V, Wesche J, Muehlenberg K, Greinacher A, Bakchoul T. Flucloxacillin-induced immune thrombocytopenia. Transfusion. 2016;56(1):67-72.

Fuhrmann J, Jouni R, Alex J, Zollner H, Wesche J, Greinacher A, Bakchoul T. Assessment of human platelet survival in the NOD/SCID mouse model: technical considerations. Transfusion. 2016;56(6):1370-6.

Bakchoul T, Warkentin TE. Safe bridging to warfarin in heparin-induced thrombocytopenia. Thrombosis research. 2016;144:226-8.

• Bakchoul T, Sachs UJ. Platelet destruction in immune thrombocytopenia. Understanding the mechanisms. Hamostaseologie. 2016;36(3):187-94.

Bakchoul T, Jouni R, Warkentin TE. Protamine (heparin)-induced thrombocytopenia: a review of the serological and clinical features associated with anti-protamine/heparin antibodies. Journal of thrombosis and haemostasis : JTH. 2016;14(9):1685-95.

Bakchoul T, Greinacher A, Warkentin TE. Heparin-induced thrombocytopenia in 2017 and beyond. Thrombosis and haemostasis. 2016;116(5):781-2.

Bakchoul T. An update on heparin-induced thrombocytopenia: diagnosis and management. Expert Opin Drug Saf. 2016;15(6):787-97.

• Bakchoul T, Nowak-Harnau S. Aktuelle Aspekte der heparininduzierten Thrombozytopenie. Kardiologie up2date 2016, 11-14.

• Für das Jahr 2015 wurden dem Webteam keine Publikationen eingereicht.
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• Bakchoul T, Assfalg V, Zöllner H, Evert M, Novotny A, Matevossian E, Friess H, Hartmann D, Hron G, Althaus K, Greinacher A, Hüser N. Anti-platelet factor 4/heparin antibodies in patients with impaired graft function after liver transplantation. J Thromb Haemost. 2014 Jun;12(6):871-8. doi: 10.1111/jth.12569. PubMed PMID: 24655935.

• Hron G, Knutson F, Thiele T, Althaus K, Busemann C, Friesecke S, Greinacher A, Lubenow N. Alternative diagnosis to heparin-induced thrombocytopenia in two critically ill patients despite a positive PF4/heparin-antibody test. Ups J Med Sci. 2013 Nov;118(4):279-84. doi: 10.3109/03009734.2013.838811. PubMed PMID: 24102149; PubMed Central PMCID: PMC4190887.

• Althaus K, Hron G, Strobel U, Abbate R, Rogolino A, Davidson S, Greinacher A, Bakchoul T. Evaluation of automated immunoassays in the diagnosis of heparin induced thrombocytopenia. Thromb Res. 2013 Mar;131(3):e85-90. doi: 10.1016/j.thromres.2013.01.005. Epub 2013 Jan 23. PubMed PMID: 23351665.

• Thiele T, Sümnig A, Hron G, Müller C, Althaus K, Schroeder HW, Greinacher A. Platelet transfusion for reversal of dual antiplatelet therapy in patients requiring urgent surgery: a pilot study. J Thromb Haemost. 2012 May;10(5):968-71. doi: 10.1111/j.1538-7836.2012.04699.x. PubMed PMID: 22429740.

• Gröpper S, Althaus K, Najm J, Haase S, Aul C, Greinacher A, Giagounidis A. A patient with Fechtner syndrome successfully treated with romiplostim. Thromb Haemost. 2012 Mar;107(3):590-1. doi: 10.1160/TH11-07-0474. Epub 2012 Jan 25. PubMed PMID: 22273764.

• Althaus K, Strobel U, Warkentin TE, Greinacher A. Combined use of the high heparin step and optical density to optimize diagnostic sensitivity and specificity of an anti-PF4/heparin enzyme-immunoassay. Thromb Res. 2011 Sep;128(3):256-60. doi: 10.1016/j.thromres.2011.05.003. Epub 2011 May 28. PubMed PMID: 21620439.

• Althaus K, Najm J, Greinacher A. MYH9 related platelet disorders – often unknown and misdiagnosed. Klin Padiatr. 2011 May;223(3):120-5. doi: 10.1055/s-0031-1275664. Epub 2011 May 12. Review. PubMed PMID: 21567368.

• Althaus K, Greinacher A. MYH-9 Related Platelet Disorders: Strategies for Management and Diagnosis. Transfus Med Hemother. 2010;37(5):260-267. Epub 2010 Sep 15. PubMed PMID: 21113248; PubMed Central PMCID: PMC2980510.

• Thiele T, Althaus K, Greinacher A. [Heparin-induced thrombocytopenia]. Internist (Berl). 2010 Sep;51(9):1127-32, 1134-5. doi: 10.1007/s00108-010-2594-5. Review. German. PubMed PMID: 20694716.

• Greinacher A, Ittermann T, Bagemühl J, Althaus K, Fürll B, Selleng S, Lubenow N, Schellong S, Sheppard JI, Warkentin TE. Heparin-induced thrombocytopenia: towards standardization of platelet factor 4/heparin antigen tests. J Thromb Haemost. 2010 Sep;8(9):2025-31. doi: 10.1111/j.1538-7836.2010.03974.x. PubMed PMID: 20626620.

• Greinacher A, Althaus K, Krauel K, Selleng S. Heparin-induced thrombocytopenia. Hamostaseologie. 2010 Jan;30(1):17-8, 20-8. Review. PubMed PMID: 20162249.

• Althaus K, Greinacher A. MYH9-related platelet disorders. Semin Thromb Hemost. 2009 Mar;35(2):189-203. doi: 10.1055/s-0029-1220327. Epub 2009 Apr 30. Review. PubMed PMID: 19408192.

• Pauzner R, Greinacher A, Selleng K, Althaus K, Shenkman B, Seligsohn U. False-positive tests for heparin-induced thrombocytopenia in patients with antiphospholipid syndrome and systemic lupus erythematosus. J Thromb Haemost. 2009 Jul;7(7):1070-4. doi: 10.1111/j.1538-7836.2009.03335.x. Epub 2009 Mar 5. PubMed PMID: 19291166.

• Rummler S, Althaus K, Maak B, Barz D. A case report of successful treatment with immunoadsorption onto protein A in mixed connective tissue disease in childhood. Ther Apher Dial. 2008 Aug;12(4):337-42. doi: 10.1111/j.1744-9987.2008.00597.x. PubMed PMID: 18789123.

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