LISTE DER PUBLIKATIONEN AUS DER TRANSFUSIONSMEDIZIN

• Ziemann M, Altermann W, Angert K, Arns W, Bachmann A, Bakchoul T, Banas B, von Borstel A, Budde K, Ditt V, Einecke G, Eisenberger U, Feldkamp T, Görg S, Guthoff M, Habicht A, Hallensleben M, Heinemann FM, Hessler N, Hugo C, Kaufmann M, Kauke T, Koch M, König IR, Kurschat C, Lehmann C, Marget M, Mühlfeld A, Nitschke M, Pego da Silva L, Quick C, Rahmel A, Rath T, Reinke P, Renders L, Sommer F, Spriewald B, Staeck O, Stippel D, Süsal C, Thiele B, Zecher D, Lachmann N. Preformed Donor-Specific HLA Antibodies in Living and Deceased Donor Transplantation: A Multicenter Study. Clin J Am Soc Nephrol. 2019 Jul 5

• Althaus, K. et al. Diagnose der Thrombozytenfunktionsstörungen Transfusionsmedizin 2019; 9:96 -108

• Althaus K, Zieger B, Bakchoul T, Jurk K. Standardization of Light Transmission Aggregometry for Diagnosis of Platelet Disorders: An Inter-Laboratory External Quality Assessment. Thromb Haemost. 2019 Jul.

• Baker JM, Shehata N, Bussel J, Murphy MF, Greinacher A, Bakchoul T, Massey E, Lieberman L, Landry D, Tanael S, Arnold DM, Baidya S, Bertrand G, Kjaer M, Kaplan C, Kjeldsen-Kragh J, Oepkes D, Savoia H, Ryan G, Hume H. Postnatal intervention for the treatment of FNAIT: a systematic review.J Perinatol. 2019 Apr 10.

• Lieberman L, Greinacher A, Murphy MF, Bussel J, Bakchoul T, Corke S, Kjaer M, Kjeldsen-Kragh J, Bertrand G, Oepkes D, Baker JM, Hume H, Massey E, Kaplan C, Arnold DM, Baidya S, Ryan G, Savoia H, Landry D, Shehata N. Fetal and neonatal alloimmune thrombocytopenia: recommendations for evidence-based practice, an international approach. Br J Haematol. 2019 May.

Marini I, Bakchoul T. Pathophysiology of Autoimmune Thrombocytopenia: Current Insight with a Focus on Thrombopoiesis. Hamostaseologie. 2019 Feb 25.

Vollenberg R, Jouni R, Norris PAA, Burg-Roderfeld M, Cooper N, Rummel MJ, Bein G, Marini I, Bayat B, Burack R, Lazarus AH, Bakchoul T, Sachs UJ. Glycoprotein V is a relevant immune target in patients with immune thrombocytopenia. Haematologica. 2019 Mar 28. pii: haematol.2018.211086. doi: 10.3324/haematol.2018.211086. PMID: 30923095.

Althaus K, Pelzl L, Hidiatov O, Amiral J, Marini I and Bakchoul T. Evaluation of a flow cytometer-based functional assay using platelet-rich plasma in the diagnosis of heparin-induced thrombocytopenia. Thrombosis Research, in press.

Eekels JJM, Althaus K, Bakchoul T, Kroll H, Kiefel V, Nazy I, Lee LS, Sachs UJ, Warkentin TE, Greinacher A. An international External Quality Assessment for laboratory diagnosis of Heparin-Induced Thrombocytopenia. J Thromb Haemost. 2019 Jan 14. doi: 10.1111/jth.14383. [Epub ahead of print]

Taran FA, Schöller D, Rall K, Nadalin S, Königsrainer A, Henes M, Bösmüller H, Fend F, Nikolaou K, Notohamiprodjo M, Grasshoff C, Heim E, Zipfel S, Schäffeler N, Bakchoul T, Heyne N, Guthoff M, Krämer B, Reisenauer C, Hoopmann M, Kagan KO, Brännström M, Wallwiener D, Brucker SY. Screening and evaluation of potential recipients and donors for living donor uterus transplantation: results from a single-center observational study. Fertil Steril. 2019 Jan;111(1):186-193. doi: 10.1016/j.fertnstert.2018.09.010.

Andres O, König EM, Althaus K, Bakchoul T, Bugert P, Eber S, Knöfler R, Kunstmann E, Manukjan G, Meyer O, Strauß G, Streif W, Thiele T, Wiegering V, Klopocki E, Schulze H. Use of Targeted High-Throughput Sequencing for Genetic Classification of Patients with Bleeding Diathesis and Suspected Platelet Disorder. TH Open. 2018 Dec 30.

Strunk D, Lozano M, Marks DC, Loh YS, Gstraunthaler G, Schennach H, Rohde E, Laner-Plamberger S, Oller M, Nystedt J, Lotfi R, Rojewski M, Schrezenmeier H, Bieback K, Schafer R, Bakchoul T, Waidmann M, Jonsdottir-Buch SM, Montazeri H, Sigurjonsson OE, Iudicone P, Fioravanti D, Pierelli L, Introna M, Capelli C, Falanga A, Takanashi M, Lopez-Villar O, Burnouf T, Reems JA, Pierce J, Preslar AM, Schallmoser K. International Forum on GMP-grade human platelet lysate for cell propagation. Vox sanguinis. 2018;113(1):e1-e25.

• Strunk D, Lozano M, Marks DC, Loh YS, Gstraunthaler G, Schennach H, Rohde E, Laner-Plamberger S, Oller M, Nystedt J, Lotfi R, Rojewski M, Schrezenmeier H, Bieback K, Schafer R, Bakchoul T, Waidmann M, Jonsdottir-Buch SM, Montazeri H, Sigurjonsson OE, Iudicone P, Fioravanti D, Pierelli L, Introna M, Capelli C, Falanga A, Takanashi M, Lomicronpez-Villar O, Burnouf T, Reems JA, Pierce J, Preslar AM, Schallmoser K. International Forum on GMP-grade human platelet lysate for cell propagation: summary. Vox sanguinis. 2018;113(1):80-7.

Marini I, Aurich K, Jouni R, Nowak-Harnau S, Hartwich O, Greinacher A, Thiele T, Bakchoul T. Cold storage of platelets in additive solution: The impact of residual plasma in apheresis platelet concentrates. Haematologica. 2018.

• Taran F, Schöller D, Königsrainer A, Fend F, Nikolaou K, Rosenberger P, Bakchoul T, Heyne P, Wallwiener D, Brucker S. Screening and evaluation of potential recipients and living donors for uterus transplantation: results from an observational study. Fertility accepted 2018.

Petermann R, Bakchoul T, Curtis B, Miyata S, Arnold D. Investigations for fetal and neonatal alloimmune thrombocytopenia: communication from the SSC of the ISTH. Journal of Thrombosis and Haemostasis, 2018, 16: 1–4.

Werner S, Pichler P, Enkel S, Bakchoul T, Horger. Dual-energy CT for liver iron quantification in patients with haematological disorders. European Radiology 2018 accepted. • Bakchoul T, Marini I. Drug-associated thrombocytopenia. Hematology 2018. Accepted.

• Bakchoul T, Marini I. Drug-associated thrombocytopenia. Hematology 2018.

Zlamal J, Bakchoul T. Acquired immune thrombocytopenia: An update on pathophysiology, diagnosis and management. Annals of Blood 2018. Accepted.

• Marini I, Althaus K, Bakchoul T. Ex vivo Thrombopoese: Könnte das Blutplättchen im Labor produziert werden? Hämotherapie 29/2018.

Marini I, Bakchoul T. Pathophysiology of autoimmune thrombocytopenia: Current insight with a focus on thrombopoiesis. Hämostaseologie 2018. Accepted.

Kjaer M, Bertrand G, Bakchoul T, Massey E, Baker JM, Lieberman L, Tanael S, Greinacher A, Murphy MF, Arnold DM, Baidya S, Bussel J, Hume H, Kaplan C, Oepkes D, Ryan G, Savoia H, Shehata N, Kjeldsen-Kragh J; Maternal HPA-1a antibody level and its role in predicting the severity of Fetal/Neonatal Alloimmune Thrombocytopenia: a systematic review. Vox Sang. 2018 Nov 22. doi: 10.1111/vox.12725. [Epub ahead of print]

Siegel G, Fleck E, Elser S, Hermanutz-Klein U, Waidmann M, Northoff H, Seifried E, Schäfer R. Manufacture of endothelial colony-forming progenitor cells from steady-state peripheral blood leukapheresis using pooled human platelet lysate. Transfusion. 2018 May;58(5):1132-1142. doi: 10.1111/trf.14541. Epub 2018 Feb 22.

Bariana TK, Labarque V, Heremans J, Thys C, De Reys M, Greene D, Jenkins B, Grassi L, Seyres D, Burden F, Whitehorn D, Shamardina O, Papadia S, Gomez K; NIHR BioResource, Van Geet C, Koulman A, Ouwehand WH, Ghevaert C, Frontini M, Turro E, Freson K. Sphingolipid dysregulation due to lack of functional KDSR impairs proplatelet formation causing thrombocytopenia. Haematologica. 2018 Nov 22. pii: haematol.2018.204784. doi: 10.3324/haematol.2018.204784. [Epub ahead of print]

Revel-Vilk S, Shai E, Turro E, Jahshan N, Hi-Am E, Spectre G, Daum H, Kalish Y, Althaus K, Greinacher A, Kaplinsky C, Izraeli S, Mapeta R, Deevi SVV, Jarocha D, Ouwehand WH, Downes K, Poncz M, Varon D, Lambert MP. GNE variants causing autosomal recessive macrothrombocytopenia without associated muscle wasting. Blood. 2018 Oct 25;132(17):1851-1854. doi: 10.1182/blood-2018-04-845545. Epub 2018 Aug 31. PubMed PMID: 30171045; PubMed Central PMCID: PMC6202914.

• Marini I, Athaus K, Bakchoul T. Ex vivo Thrombopoiese: Könnten Blutplättchen im Labor produziert werden?. Hämotherapie 30/2018.

Siegel G, Fleck E, Elser S, Hermanutz-Klein U, Waidmann M, Northoff H, Seifried E, Schäfer R. Manufacture of endothelial colony-forming progenitor cells from steady-state peripheral blood leukapheresis using pooled human platelet lysate Transfusion. 2018 May;58(5):1132-1142. doi: 10.1111/trf.14541. Epub 2018 Feb 22.

Zollner H, Jouni R, Panzer S, Khadour A, Janzen L, Wesche J, Ten Berg M, Schellong S, Heinken A, Greinacher A, Bakchoul T. Platelet activation in the presence of neutral protamine Hagedorn insulin: a new feature of antibodies against protamine/heparin complexes. Journal of thrombosis and haemostasis : JTH. 2017;15(1):176-84.

Bakchoul T, Wanner Y, Nowak-Harnau S. Heparininduzierte Thrombozytopenie: Ein Update über die Anwendung von direkten oralen Antikoagulanzien. Z GfäßMed 2017;14(4-9).

• Bakchoul T, Hinz A. Diagnostik von angeborenen und erworbenen Thrombozyten-Erkrankungen. Hämotherapie 28/2017.

Winkelhorst D, Murphy MF, Greinacher A, Shehata N, Bakchoul T, Massey E, Baker J, Lieberman L, Tanael S, Hume H, Arnold DM, Baidya S, Bertrand G, Bussel J, Kjaer M, Kaplan C, Kjeldsen-Kragh J, Oepkes D, Ryan G. Antenatal management in fetal and neonatal alloimmune thrombocytopenia: a systematic review. Blood. 2017;129(11):1538-47.

Schulze H, Schlagenhauf A, Manukjan G, Beham-Schmid C, Andres O, Klopocki E, Konig EM, Haidl H, Panzer S, Althaus K, Muntean WE, Schwinger W, Urban C, Greinacher A, Bakchoul T, Seidel MG. Recessive grey platelet-like syndrome with unaffected erythropoiesis in the absence of the splice isoform GFI1B-p37. Haematologica. 2017;102(9):e375-e8.

Greinacher A, Pecci A, Kunishima S, Althaus K, Nurden P, Balduini CL, Bakchoul T. Diagnosis of inherited platelet disorders on a blood smear: a tool to facilitate worldwide diagnosis of platelet disorders. Journal of thrombosis and haemostasis : JTH. 2017;15(7):1511-21.

Farm M, Bakchoul T, Frisk T, Althaus K, Odenrick A, Norberg EM, Berndtsson M, Antovic JP. Evaluation of a diagnostic algorithm for Heparin-Induced Thrombocytopenia. Thrombosis research. 2017;152:77-81.

Aurich K, Wesche J, Palankar R, Schluter R, Bakchoul T, Greinacher A. Magnetic Nanoparticle Labeling of Human Platelets from Platelet Concentrates for Recovery and Survival Studies. ACS Appl Mater Interfaces. 2017;9(40):34666-73.

• Platelet Lysate: The Better Choice for Jaw Periosteal Cell Mineralization. Wanner Y, Umrath F, Waidmann M, Reinert S, Alexander D. Stem Cells Int. 2017;2017:8303959. doi: 10.1155/2017/8303959. Epub 2017 Dec 17.

• Farm M, Bakchoul T, Frisk T, Althaus K, Odenrick A, Norberg EM, Berndtsson M, Antovic JP. Evaluation of a diagnostic algorithm for Heparin-Induced Thrombocytopenia. Thromb Res. 2017 Apr;152:77-81. doi:10.1016/j.thromres.2017.02.015. Epub 2017 Feb 24. PubMed PMID: 28262567.

Marini I, Siegemund M, Hutt M, Kontermann RE, Pfizenmaier K. Antitumor Activity of a Mesenchymal Stem Cell Line Stably Secreting a Tumor-Targeted TNF-Related Apoptosis-Inducing Ligand Fusion Protein..Front Immunol. 2017 May 11;8:536. doi: 10.3389/fimmu.2017.00536. eCollection 2017.PMID:28553285

Wanner Y, Umrath F, Waidmann M, Reinert S, Alexander D. Platelet Lysate: The Better Choice for Jaw Periosteal Cell Mineralization. Stem Cells Int. 2017;2017:8303959. doi: 10.1155/2017/8303959. Epub 2017 Dec 17.

Turro E, Greene D, Wijgaerts A, Thys C, Lentaigne C, Bariana TK, Westbury SK, Kelly AM, Selleslag D, Stephens JC, Papadia S, Simeoni I, Penkett CJ, Ashford S, Attwood A, Austin S, Bakchoul T, Collins P, Deevi SV, Favier R, Kostadima M, Lambert MP, Mathias M, Millar CM, Peerlinck K, Perry DJ, Schulman S, Whitehorn D, Wittevrongel C, Consortium B-B, De Maeyer M, Rendon A, Gomez K, Erber WN, Mumford AD, Nurden P, Stirrups K, Bradley JR, Raymond FL, Laffan MA, Van Geet C, Richardson S, Freson K, Ouwehand WH. A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies. Sci Transl Med. 2016;8(328):328ra30.

Stritt S, Nurden P, Turro E, Greene D, Jansen SB, Westbury SK, Petersen R, Astle WJ, Marlin S, Bariana TK, Kostadima M, Lentaigne C, Maiwald S, Papadia S, Kelly AM, Stephens JC, Penkett CJ, Ashford S, Tuna S, Austin S, Bakchoul T, Collins P, Favier R, Lambert MP, Mathias M, Millar CM, Mapeta R, Perry DJ, Schulman S, Simeoni I, Thys C, Consortium B-B, Gomez K, Erber WN, Stirrups K, Rendon A, Bradley JR, van Geet C, Raymond FL, Laffan MA, Nurden AT, Nieswandt B, Richardson S, Freson K, Ouwehand WH, Mumford AD. A gain-of-function variant in DIAPH1 causes dominant macrothrombocytopenia and hearing loss. Blood. 2016;127(23):2903-14.

Santoso S, Wihadmadyatami H, Bakchoul T, Werth S, Al-Fakhri N, Bein G, Kiefel V, Zhu J, Newman PJ, Bayat B, Sachs UJ. Antiendothelial alphavbeta3 Antibodies Are a Major Cause of Intracranial Bleeding in Fetal/Neonatal Alloimmune Thrombocytopenia. Arterioscler Thromb Vasc Biol. 2016;36(8):1517-24.

• Nagler M, Bakchoul T. Clinical and laboratory tests for the diagnosis of heparin-induced thrombocytopenia. Thrombosis and haemostasis. 2016;116(5):823-34.

Morel-Kopp MC, Mullier F, Gkalea V, Bakchoul T, Minet V, Elalamy I, Ward CM, subcommittee on platelet i. Heparin-induced multi-electrode aggregometry method for heparin-induced thrombocytopenia testing: communication from the SSC of the ISTH. Journal of thrombosis and haemostasis : JTH. 2016;14(12):2548-52.

Krauel K, Schulze A, Jouni R, Hackbarth C, Hietkamp B, Selleng S, Koster A, Jensch I, van der Linde J, Schwertz H, Bakchoul T, Hundt M, Greinacher A. Further insights into the anti-PF4/heparin IgM immune response. Thrombosis and haemostasis. 2016;115(4):752-61.

Jouni R, Zollner H, Khadour A, Wesche J, Grotevendt A, Brandt S, Delcea M, Krauel K, Schwertz H, Sachs UJ, Greinacher A, Bakchoul T. Partially desulfated heparin modulates the interaction between anti-protamine/heparin antibodies and platelets. Thrombosis and haemostasis. 2016;115(2):324-32.

Jatzlauk G, Althaus K, Strobel U, Kiefel V, Wesche J, Muehlenberg K, Greinacher A, Bakchoul T. Flucloxacillin-induced immune thrombocytopenia. Transfusion. 2016;56(1):67-72.

Fuhrmann J, Jouni R, Alex J, Zollner H, Wesche J, Greinacher A, Bakchoul T. Assessment of human platelet survival in the NOD/SCID mouse model: technical considerations. Transfusion. 2016;56(6):1370-6.

Bakchoul T, Warkentin TE. Safe bridging to warfarin in heparin-induced thrombocytopenia. Thrombosis research. 2016;144:226-8.

• Bakchoul T, Sachs UJ. Platelet destruction in immune thrombocytopenia. Understanding the mechanisms. Hamostaseologie. 2016;36(3):187-94.

Bakchoul T, Jouni R, Warkentin TE. Protamine (heparin)-induced thrombocytopenia: a review of the serological and clinical features associated with anti-protamine/heparin antibodies. Journal of thrombosis and haemostasis : JTH. 2016;14(9):1685-95.

Bakchoul T, Greinacher A, Warkentin TE. Heparin-induced thrombocytopenia in 2017 and beyond. Thrombosis and haemostasis. 2016;116(5):781-2.

Bakchoul T. An update on heparin-induced thrombocytopenia: diagnosis and management. Expert Opin Drug Saf. 2016;15(6):787-97.

• Bakchoul T, Nowak-Harnau S. Aktuelle Aspekte der heparininduzierten Thrombozytopenie. Kardiologie up2date 2016, 11-14.

• Für das Jahr 2015 wurden dem Webteam keine Publikationen eingereicht.
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• Bakchoul T, Assfalg V, Zöllner H, Evert M, Novotny A, Matevossian E, Friess H, Hartmann D, Hron G, Althaus K, Greinacher A, Hüser N. Anti-platelet factor 4/heparin antibodies in patients with impaired graft function after liver transplantation. J Thromb Haemost. 2014 Jun;12(6):871-8. doi: 10.1111/jth.12569. PubMed PMID: 24655935.

• Hron G, Knutson F, Thiele T, Althaus K, Busemann C, Friesecke S, Greinacher A, Lubenow N. Alternative diagnosis to heparin-induced thrombocytopenia in two critically ill patients despite a positive PF4/heparin-antibody test. Ups J Med Sci. 2013 Nov;118(4):279-84. doi: 10.3109/03009734.2013.838811. PubMed PMID: 24102149; PubMed Central PMCID: PMC4190887.

• Althaus K, Hron G, Strobel U, Abbate R, Rogolino A, Davidson S, Greinacher A, Bakchoul T. Evaluation of automated immunoassays in the diagnosis of heparin induced thrombocytopenia. Thromb Res. 2013 Mar;131(3):e85-90. doi: 10.1016/j.thromres.2013.01.005. Epub 2013 Jan 23. PubMed PMID: 23351665.

• Thiele T, Sümnig A, Hron G, Müller C, Althaus K, Schroeder HW, Greinacher A. Platelet transfusion for reversal of dual antiplatelet therapy in patients requiring urgent surgery: a pilot study. J Thromb Haemost. 2012 May;10(5):968-71. doi: 10.1111/j.1538-7836.2012.04699.x. PubMed PMID: 22429740.

• Gröpper S, Althaus K, Najm J, Haase S, Aul C, Greinacher A, Giagounidis A. A patient with Fechtner syndrome successfully treated with romiplostim. Thromb Haemost. 2012 Mar;107(3):590-1. doi: 10.1160/TH11-07-0474. Epub 2012 Jan 25. PubMed PMID: 22273764.

• Althaus K, Strobel U, Warkentin TE, Greinacher A. Combined use of the high heparin step and optical density to optimize diagnostic sensitivity and specificity of an anti-PF4/heparin enzyme-immunoassay. Thromb Res. 2011 Sep;128(3):256-60. doi: 10.1016/j.thromres.2011.05.003. Epub 2011 May 28. PubMed PMID: 21620439.

• Althaus K, Najm J, Greinacher A. MYH9 related platelet disorders – often unknown and misdiagnosed. Klin Padiatr. 2011 May;223(3):120-5. doi: 10.1055/s-0031-1275664. Epub 2011 May 12. Review. PubMed PMID: 21567368.

• Althaus K, Greinacher A. MYH-9 Related Platelet Disorders: Strategies for Management and Diagnosis. Transfus Med Hemother. 2010;37(5):260-267. Epub 2010 Sep 15. PubMed PMID: 21113248; PubMed Central PMCID: PMC2980510.

• Thiele T, Althaus K, Greinacher A. [Heparin-induced thrombocytopenia]. Internist (Berl). 2010 Sep;51(9):1127-32, 1134-5. doi: 10.1007/s00108-010-2594-5. Review. German. PubMed PMID: 20694716.

• Greinacher A, Ittermann T, Bagemühl J, Althaus K, Fürll B, Selleng S, Lubenow N, Schellong S, Sheppard JI, Warkentin TE. Heparin-induced thrombocytopenia: towards standardization of platelet factor 4/heparin antigen tests. J Thromb Haemost. 2010 Sep;8(9):2025-31. doi: 10.1111/j.1538-7836.2010.03974.x. PubMed PMID: 20626620.

• Greinacher A, Althaus K, Krauel K, Selleng S. Heparin-induced thrombocytopenia. Hamostaseologie. 2010 Jan;30(1):17-8, 20-8. Review. PubMed PMID: 20162249.

• Althaus K, Greinacher A. MYH9-related platelet disorders. Semin Thromb Hemost. 2009 Mar;35(2):189-203. doi: 10.1055/s-0029-1220327. Epub 2009 Apr 30. Review. PubMed PMID: 19408192.

• Pauzner R, Greinacher A, Selleng K, Althaus K, Shenkman B, Seligsohn U. False-positive tests for heparin-induced thrombocytopenia in patients with antiphospholipid syndrome and systemic lupus erythematosus. J Thromb Haemost. 2009 Jul;7(7):1070-4. doi: 10.1111/j.1538-7836.2009.03335.x. Epub 2009 Mar 5. PubMed PMID: 19291166.

• Rummler S, Althaus K, Maak B, Barz D. A case report of successful treatment with immunoadsorption onto protein A in mixed connective tissue disease in childhood. Ther Apher Dial. 2008 Aug;12(4):337-42. doi: 10.1111/j.1744-9987.2008.00597.x. PubMed PMID: 18789123.